Molecular pathogenesis of inflammatory bowel disease: genotypes, phenotypes and personalized medicine

P Goyette, C Labbé, TT Trinh, RJ Xavier… - Annals of …, 2007 - Taylor & Francis
… Potential molecular pathways involved in inflammatory bowel disease(IBD) pathogenesis.
In healthy individuals, bacterial invasions trigger cascades of immune events leading to …

[HTML][HTML] Inflammatory bowel disease: pathogenesis

YZ Zhang, YY Li - World journal of gastroenterology: WJG, 2014 - ncbi.nlm.nih.gov
… with genetic elements in the pathogenesis of IBD. Meanwhile, the … to play a major role in the
pathogenesis of IBD, as new studies in … IBD pathogenesis sheds lights on relevant disease

Dysplastic lesions in inflammatory bowel disease: molecular pathogenesis to morphology

KA Matkowskyj, ZE Chen, MS Rao… - Archives of pathology …, 2013 - meridian.allenpress.com
… , we outline the epidemiologic and molecular pathogenesis of the risk for colorectal cancer
… lesions, by using morphology in conjunction with molecular pathways, and discuss the “field …

Pathogenesis of inflammatory bowel disease

JA Katz, J Itoh, C Fiocchi - Current opinion in gastroenterology, 1999 - journals.lww.com
… This certainly appears to be the case for inflammatory bowel disease (IBD). The
pathogenesis of both forms of IBD, Crohn’s disease (CD) and ulcerative colitis (UC), involves an …

Overview of molecular pathways in inflammatory bowel disease associated with colorectal cancer development

SA Azer - European journal of gastroenterology & hepatology, 2013 - journals.lww.com
… Colorectal cancer (CRC) is the most common malignant complication in patients who have
inflammatory bowel disease (IBD). The cumulative risks for developing CRC after 10, 20, and …

[HTML][HTML] Inflammatory bowel disease: genetics, epigenetics, and pathogenesis

I Loddo, C Romano - Frontiers in immunology, 2015 - frontiersin.org
Inflammatory bowel diseases (IBDs) are complex, multifactorial … the pathogenesis. Epidemiological
evidence for a genetic contribution is defined: 15% of patients with Crohn’s Disease (…

Animal models of intestinal inflammation: new insights into the molecular pathogenesis and immunotherapy of inflammatory bowel disease

S Wirtz, MF Neurath - International journal of colorectal disease, 2000 - Springer
Inflammatory bowel diseases (IBDs) in humans are complex chronic inflammatory disorders
of largely unknown cause. Several mouse models that in some respects resemble human …

Genetics and pathogenesis of inflammatory bowel disease

B Khor, A Gardet, RJ Xavier - Nature, 2011 - nature.com
… Inflammatory bowel disease (IBD) comprises the chronic relapsing inflammatory disorders
Crohn's disease and ulcerative colitis. Family history is a risk factor for developing IBD, with a …

Inflammatory bowel disease: etiology and pathogenesis

C Fiocchi - Gastroenterology, 1998 - Elsevier
… the clinician and the investigator, but few are as complex and enigmatic as inflammatory
bowel disease (IBD). Crohn's disease (CD) and ulcerative colitis (UC) have been known for well …

Unravelling the pathogenesis of inflammatory bowel disease

RJ Xavier, DK Podolsky - Nature, 2007 - nature.com
… the understanding of the molecular pathogenesis of inflammatory bowel disease (IBD)
have … , and innate and adaptive immunity in disease pathogenesis. Second, efforts directed …