Role of toll-like receptors in inflammatory bowel disease

N Kordjazy, A Haj-Mirzaian, A Haj-Mirzaian… - Pharmacological …, 2018 - Elsevier
… Inflammatory bowel disease (IBD) is the chronic inflammation of … Expression of the innate
immune receptors plays a key role in … It is well-known that TLRs are essential components of …

The role of innate immunity receptors in the pathogenesis of inflammatory bowel disease

PP Elia, YFM Tolentino, C Bernardazzi… - Mediators of …, 2015 - Wiley Online Library
receptors dysfunction that result in the persistent inflammation in inflammatory bowel disease
… In fact, not only whole microbes, but also diffusible components can interact with the PRRs. …

Evaluation of interleukin-6 and its soluble receptor components sIL-6R and sgp130 as markers of inflammation in inflammatory bowel diseases

S Nikolaus, GH Waetzig, S Butzin, M Ziolkiewicz… - … of colorectal disease, 2018 - Springer
… inflammatory bowel diseases (IBD). As published serum levels of IL-6 and its soluble receptors
… levels as markers of disease activity in Crohn’s disease (CD) and ulcerative colitis (UC). …

Toll-like receptors in inflammatory bowel diseases: a decade later

E Cario - Inflammatory bowel diseases, 2010 - academic.oup.com
… Differential alteration of Toll-like receptor (TLR) expression in inflammatory bowel disease
(IBD) was first described 10 years ago. Since then, studies from many groups have led to the …

Pattern recognition receptors—molecular orchestrators of inflammation in inflammatory bowel disease

D Walsh, J McCarthy, C O'Driscoll, S Melgar - Cytokine & growth factor …, 2013 - Elsevier
… PRRs represent a group of germline encoded receptors responsible for the detection of
conserved microbial PAMPs, including bacterial and fungal cell wall components and viral …

Mutations in pattern recognition receptor genes modulate seroreactivity to microbial antigens in patients with inflammatory bowel disease

L Henckaerts, M Pierik, M Joossens, M Ferrante… - Gut, 2007 - gut.bmj.com
… The TLR4 gene encodes the TLR4 receptor, a transmembrane receptor binding the
lipopolysaccharide component of Gram-negative bacteria through an extracellular domain …

Bile acids activated receptors in inflammatory bowel disease

M Biagioli, S Marchianò, A Carino, C Di Giorgio… - Cells, 2021 - mdpi.com
… In conclusion, bile acids and their receptors are an essential component of the chemical
communications between the intestinal microbiota and the host immune system. Altered bile …

Role of the xenobiotic receptor in inflammatory bowel disease

R Arsenescu, V Arsenescu, J Zhong… - … bowel diseases, 2011 - academic.oup.com
… Gene-environment interplay modulates inflammatory bowel diseases (IBD). Dioxin-like
compounds can activate the aryl hydrocarbon receptor (AhR) and alter macrophage function as …

The role of extracellular matrix components in inflammatory bowel diseases

A Derkacz, P Olczyk, K Olczyk… - Journal of Clinical …, 2021 - mdpi.com
component of the extracellular matrix, increases. On the other hand, in chronic inflammatory
conditions such as inflammatory bowel diseases (… responses via specific receptors, induces …

[HTML][HTML] Immunopathology of inflammatory bowel disease

KL Wallace, LB Zheng, Y Kanazawa… - World journal of …, 2014 - ncbi.nlm.nih.gov
receptor for muramyl dipeptide (MDP), a component of the bacterial wall peptidoglycans.
Mice lacking intracellular pattern recognition receptors, … pattern recognition receptors, might …