Evaluation of interleukin-6 and its soluble receptor components sIL-6R and sgp130 as markers of inflammation in inflammatory bowel diseases
S Nikolaus, GH Waetzig, S Butzin, M Ziolkiewicz… - … of colorectal disease, 2018 - Springer
… As published serum levels of IL-6 and its soluble receptors sIL-6R and sgp130 in IBD are …
evaluated IL-6, sIL-6R and sgp130 levels as markers of disease activity in Crohn’s disease (CD…
evaluated IL-6, sIL-6R and sgp130 levels as markers of disease activity in Crohn’s disease (CD…
Interleukin‐6 and soluble interleukin‐6 receptor in the colonic mucosa of inflammatory bowel disease
T Hosokawa, K Kusugami, K Ina, T Ando… - Journal of …, 1999 - Wiley Online Library
… intestinal sIL-6R levels in patients with IBD and what cell types are involved in sIL-6R
secretion in the intestinal … In the present study, we examined the contents of IL-6 and sIL-6R in …
secretion in the intestinal … In the present study, we examined the contents of IL-6 and sIL-6R in …
Involvement of IL-6 in the pathogenesis of inflammatory bowel disease and colon cancer
R Atreya, MF Neurath - Clinical reviews in allergy & immunology, 2005 - Springer
… the effect of IL-6 (41). sIL-6R and circulating sIL-6R–IL-6 complexes in the serum were …
Correspondingly increased sIL6R production by cultured intestinal mononuclear cells of patients …
Correspondingly increased sIL6R production by cultured intestinal mononuclear cells of patients …
Il-6 signaling in inflammatory bowel disease: pathophysiological role and clinical relevance
J Mudter, MF Neurath - Inflammatory bowel diseases, 2007 - academic.oup.com
… When we talk about IL-6 we should consider the role of its soluble IL-6 receptor, 25 because
… in active inflammatory bowel diseases. Furthermore, antibodies to IL-6 receptor (MRA) has …
… in active inflammatory bowel diseases. Furthermore, antibodies to IL-6 receptor (MRA) has …
Soluble interleukin-6 receptors in inflammatory bowel disease: relation to circulating interleukin-6.
K Mitsuyama, A Toyonaga, E Sasaki, O Ishida, H Ikeda… - Gut, 1995 - gut.bmj.com
… However, little is known about the profile of sIL-6R in human diseases.'4 A … -6 receptor. To
our knowledge, this is the first report of in vivo levels of sIL-6R in inflammatory bowel disease. …
our knowledge, this is the first report of in vivo levels of sIL-6R in inflammatory bowel disease. …
Therapeutic strategies for targeting the IL-6/STAT3 cytokine signaling pathway in inflammatory bowel disease
K Mitsuyama, S Matsumoto, J Masuda… - Anticancer …, 2007 - ar.iiarjournals.org
… bowel disease (IBD) relies on IL-6-mediated STAT3 activation on mucosal T-cells. This review
looks at therapeutic strategies targeting the IL-6/… of IL-6R (sIL6R) and IL-6 stimulates cells …
looks at therapeutic strategies targeting the IL-6/… of IL-6R (sIL6R) and IL-6 stimulates cells …
Interleukin-6 trans-signaling in inflammatory bowel disease
K Mitsuyama, M Sata, S Rose-John - Cytokine & growth factor reviews, 2006 - Elsevier
… intestinal levels of IL-6 as well as soluble IL-6 receptor (sIL-… bowel disease (IBD), in particular
Crohn's disease and ulcerative colitis, is characterized by chronic recurrent inflammation of …
Crohn's disease and ulcerative colitis, is characterized by chronic recurrent inflammation of …
Interleukin-6 trans-signaling and colonic cancer associated with inflammatory bowel disease
S Rose-John, K Mitsuyama… - Current …, 2009 - ingentaconnect.com
… IL-6 in IBD and inflammation induced colon cancer and we will summarize the consequences
of these new results for the prospects of IL-6 … that IL-6 signaling through sIL6R controls this …
of these new results for the prospects of IL-6 … that IL-6 signaling through sIL6R controls this …
Cytokines in inflammatory bowel disease
AC Moldoveanu, M Diculescu… - Romanian Journal of …, 2015 - sciendo.com
… bowel diseases. The identification of new cytokines, as well as the changing of the pathogenesis
paradigms in inflammatory bowel diseases has … receptor IL-6 (sIL-6R) and IL-6 plays an …
paradigms in inflammatory bowel diseases has … receptor IL-6 (sIL-6R) and IL-6 plays an …
… of serum interleukin-6 and soluble interleukin-2-receptor levels with disease activity status in patients with inflammatory bowel disease: a prospective observational …
E Mavropoulou, NC Mechie, R Knoop, G Petzold… - PLoS …, 2020 - journals.plos.org
… of interleukin (IL)-6, soluble-IL-2-receptor (sIL-2R) and CRP as … There is currently no gold
standard for the monitoring of disease … none of the patients had isolated small bowel disease. …
standard for the monitoring of disease … none of the patients had isolated small bowel disease. …
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