bozozok directly represses bmp2b transcription and mediates the earliest dorsoventral asymmetry of bmp2b expression in zebrafish

TC Leung, J Bischof, I Söll, D Niessing, D Zhang… - 2003 - journals.biologists.com
Formation of the gastrula organizer requires suppression of ventralizing signals and, in fish
and frog, the need to counteract the effect of ubiquitously present maternal factors that
activate the expression of Bmps. How the balance between dorsalizing and ventralizing
factors is shifted towards organizer establishment at late blastula stages is not well
understood. Mutations in zebrafish bozozok (boz) cause severe defects in axial mesoderm
and anterior neurectoderm and affect organizer formation. The boz gene encodes the …

Bozozok directly represses bmp2b transcription and mediates the earliest dorsoventral asymmetry of bmp2b expression in zebrafish.

LTC Leung TinChung, J Bischof, I Söll, D Niessing… - 2003 - cabidigitallibrary.org
Formation of the gastrula organizer requires suppression of ventralizing signals and, in fish
and frog, the need to counteract the effect of ubiquitously present maternal factors that
activate the expression of Bmps. How the balance between dorsalizing and ventralizing
factors is shifted towards organizer establishment at late blastula stages is not well
understood. Mutations in zebrafish bozozok (boz) cause severe defects in axial mesoderm
and anterior neurectoderm and affect organizer formation. The boz gene encodes the …
以上显示的是最相近的搜索结果。 查看全部搜索结果