… by combining BRAF V600E and TERT promoter mutations in papillary thyroid cancer: genetic duet of BRAF and TERT promoter mutations in thyroid cancer mortality
… BRAF V600E andTERTpromoter mutations can coexist in papillary thyroid cancer (PTC).
This genetic duet was indicated to be involved in the aggressiveness of PTC, but its prognostic …
This genetic duet was indicated to be involved in the aggressiveness of PTC, but its prognostic …
BRAF inhibition in BRAF V600E-positive anaplastic thyroid carcinoma
AM Lim, GR Taylor, A Fellowes, L Cameron… - … Comprehensive Cancer …, 2016 - jnccn.org
… targeted monotherapy for BRAF V600E -positive anaplastic thyroid carcinomas (ATC) is not
established. We report 2 cases of BRAF V600E -positive ATC treated with a BRAF inhibitor. …
established. We report 2 cases of BRAF V600E -positive ATC treated with a BRAF inhibitor. …
BRAFV600E mutation is associated with an increased risk of nodal recurrence requiring reoperative surgery in patients with papillary thyroid cancer
… In thyroid cancer, occurrence of the BRAF V600E mutation only occurs in its papillary and
anaplastic subtypes, with a frequency of approximately 45% (range, 27–87%) in PTC patients.8…
anaplastic subtypes, with a frequency of approximately 45% (range, 27–87%) in PTC patients.8…
BRAFV600E status and clinical characteristics in solitary and multiple papillary thyroid carcinoma: experience of 512 cases at a clinical center in China
X Zheng, T Xia, L Lin, S Gao, Y Lee, Y Yu, S Wei… - World Journal of …, 2012 - Springer
… that BRAF V600E mutation occurs more frequently in aggressive PTC. The purpose of this
study was to evaluate BRAF V600E … age, large tumors and BRAF V600E mutation should be …
study was to evaluate BRAF V600E … age, large tumors and BRAF V600E mutation should be …
Patient Age–Associated Mortality Risk Is Differentiated by BRAF V600E Status in Papillary Thyroid Cancer
… an association between BRAF V600E and older … BRAF V600E might play an important role
in the effect of patient age on PTC-specific mortality, and that, in the absence of BRAF V600E, …
in the effect of patient age on PTC-specific mortality, and that, in the absence of BRAF V600E, …
Clinical significance of BRAF V600E mutation in 154 patients with thyroid nodules
L Yu, L Ma, Q Tu, YI Zhang, Y Chen… - Oncology …, 2015 - spandidos-publications.com
… of the BRAF V600E mutation in papillary thyroid carcinoma (PTC) … BRAF V600E mutation
status was analyzed in 206 thyroid … the BRAF V600E mutation with clinicopathological features. …
status was analyzed in 206 thyroid … the BRAF V600E mutation with clinicopathological features. …
BRAFV600E mutation in Turkish patients with papillary thyroid cancer: strong correlation with indicators of tumor aggressiveness
N Kurtulmus, M Duren, U Ince, M Cengiz Yakicier… - Endocrine, 2012 - Springer
… association of the BRAF V600E mutation with prognostic factors and poor clinical outcome
in papillary thyroid cancer. This meta-analysis demonstrates that the BRAF V600E mutation is …
in papillary thyroid cancer. This meta-analysis demonstrates that the BRAF V600E mutation is …
… BRAF Mutation Analysis: BRAF V600E Is Acquired Early During Tumor Development but Is Heterogeneously Distributed in a Subset of Papillary Thyroid Carcinomas
D de Biase, V Cesari, M Visani… - The Journal of …, 2014 - academic.oup.com
… Most of our knowledge on the status of BRAF V600E in thyroid cancer is based on Sanger
sequencing, which has low analytical sensitivity and does not provide quantitative information …
sequencing, which has low analytical sensitivity and does not provide quantitative information …
Surgical Results of Thyroid Nodules according to a Management Guideline Based on the BRAFV600E Mutation Status
SK Kim, TS Hwang, YB Yoo, HS Han… - The Journal of …, 2011 - academic.oup.com
… for BRAF V600E mutation in thyroid nodule, if positive, would seem to indicate a diagnosis
of malignancy with virtually 100% specificity (for either PTCs or anaplastic thyroid carcinomas…
of malignancy with virtually 100% specificity (for either PTCs or anaplastic thyroid carcinomas…
Suspicious Ultrasound Characteristics Predict BRAFV600E-Positive Papillary Thyroid Carcinoma
AS Kabaker, ME Tublin, YE Nikiforov, MJ Armstrong… - Thyroid, 2012 - liebertpub.com
… (16) reported a correlation between BRAF V600E and small tumor size… BRAF positivity.
Another study by Hwang et al. (17) also demonstrated no significant associations between BRAF …
Another study by Hwang et al. (17) also demonstrated no significant associations between BRAF …