Genome-wide alterations in gene methylation by the BRAF V600E mutation in papillary thyroid cancer cells
P Hou, D Liu, M Xing - Endocrine-related cancer, 2011 - erc.bioscientifica.com
… were observed in the expression of ERα target genes; G6PDH expression was significantly
… However, our finding suggesting a positive correlation between p27 expression and uterine …
… However, our finding suggesting a positive correlation between p27 expression and uterine …
BRAF Mutation Testing in Colorectal Cancer
SG Sharma, ML Gulley - Archives of pathology & …, 2010 - meridian.allenpress.com
… 85% have evidence of the chromosomal instability pathway of progression.5 Distinguishing
… MLH1 expression, the presence of MLH1 promoter methylation or presence of BRAF V600E …
… MLH1 expression, the presence of MLH1 promoter methylation or presence of BRAF V600E …
Clinicopathological and protein characterization of BRAF‐ and K‐RAS‐mutated colorectal cancer and implications for prognosis
I Zlobec, MP Bihl, H Schwarb… - … journal of cancer, 2010 - Wiley Online Library
… associated with tumors arising from the chromosomal instability (CIN) pathway following
the … and inflammatory-associated protein expression in patients with BRAF V600E and K-RAS …
the … and inflammatory-associated protein expression in patients with BRAF V600E and K-RAS …
Fusion-mediated chromosomal instability promotes aneuploidy patterns that resemble human tumors
L Delespaul, C Merle, T Lesluyes, P Lagarde… - Oncogene, 2019 - nature.com
… Although preliminary, our findings provide a simple model that explains how chromosomal
instability can occur in sporadic cancers without mutations that directly affect chromosome …
instability can occur in sporadic cancers without mutations that directly affect chromosome …
Spectrum of BRAF Mutations and Gene Rearrangements in Ovarian Serous Carcinoma
… BRAF V600E oncoprotein expression was assessed by immunohistochemistry on selected
… At the molecular level, HGSC exhibits widespread chromosomal instability with somatic …
… At the molecular level, HGSC exhibits widespread chromosomal instability with somatic …
Centrosome linker–induced tetraploid segregation errors link rhabdoid phenotypes and lethal colorectal cancers
A Remo, E Manfrin, P Parcesepe, A Ferrarini… - Molecular Cancer …, 2018 - AACR
… Interfering with CROCC expression in near-diploid BRAF V600E -mutant/MSI colon cancer
… of chromosome instability (CIN) were available, revealed that CROCC expression levels …
… of chromosome instability (CIN) were available, revealed that CROCC expression levels …
RNF43 mutation is associated with aggressive tumor biology along with BRAF V600E mutation in right-sided colorectal cancer
A Matsumoto, Y Shimada, M Nakano… - Oncology …, 2020 - spandidos-publications.com
… of RNF43 mutation and BRAF V600E mutation has been … invasion, and BRAF V600E mutation
were independently … , APC wild, BRAF V600E mutation, microsatellite instability-high (MSI-…
were independently … , APC wild, BRAF V600E mutation, microsatellite instability-high (MSI-…
Survival in stage II/III colorectal cancer is independently predicted by chromosomal and microsatellite instability, but not by specific driver mutations
… Microsatellite instability (MSI) is an established marker of good prognosis in colorectal cancer
(CRC). Chromosomal instability (CIN) is strongly negatively associated with MSI and has …
(CRC). Chromosomal instability (CIN) is strongly negatively associated with MSI and has …
BRAF mutation associated with other genetic events identifies a subset of aggressive papillary thyroid carcinoma
AM Costa, A Herrero, MF Fresno… - Clinical …, 2008 - Wiley Online Library
… BRAF V600E and the only one that did not, BRAF V600E was restricted to the Pt. The occurrence
of BRAF V600E … Conclusion BRAF V600E ‘alone’ does not represent a marker for poor …
of BRAF V600E … Conclusion BRAF V600E ‘alone’ does not represent a marker for poor …
Oncogenic mutation BRAF V600E changes phenotypic behavior of THLE-2 liver cells through alteration of gene expression
… In conclusion, our study demonstrates that enhanced BRAF V600E expression in hepatocytes
favors cancerous development. Therefore, further research is needed to explore the …
favors cancerous development. Therefore, further research is needed to explore the …