[HTML][HTML] Short chain fatty acids: microbial metabolites for gut-brain axis signalling

KJ O'Riordan, MK Collins, GM Moloney… - Molecular and Cellular …, 2022 - Elsevier
… -brain axis signalling has risen to prominence in recent years. Understanding the relationship
between the gut microbiota, the metabolites it produces, and the brain … -chain fatty acids (…

[HTML][HTML] Gut-brain axis: Focus on gut metabolites short-chain fatty acids

C Guo, YJ Huo, Y Li, Y Han, D Zhou - World journal of clinical …, 2022 - ncbi.nlm.nih.gov
… that short-chain fatty acids (SCFAs) exert crucial functions on the brain. The levels of SCFAs
… microbiota–gut–brain (MGB) axis, the interactions between SCFAs and MGB axis, as well as …

Short-chain fatty acids in the microbiota–gut–brain axis: role in neurodegenerative disorders and viral infections

A Majumdar, IP Siva Venkatesh… - ACS Chemical …, 2023 - ACS Publications
… The gut–brain axis (GBA) is the umbrella term to include all bidirectional communication
between the brain and gastrointestinal (GI) tract in the mammalian body. Evidence from over …

Chemogenetics defines a short-chain fatty acid receptor gut–brain axis

N Barki, D Bolognini, U Börjesson, L Jenkins, J Riddell… - Elife, 2022 - elifesciences.org
… To overcome these issues, and to define unambiguously specific roles of FFA2 and FFA3
in the actions of SCFAs within the gut–brain axis herein we have applied an integrated …

[HTML][HTML] The microbiota-gut-brain axis participates in chronic cerebral hypoperfusion by disrupting the metabolism of short-chain fatty acids

W Xiao, J Su, X Gao, H Yang, R Weng, W Ni, Y Gu - Microbiome, 2022 - Springer
… (CCH) underlies secondary brain injury following certain … gut-brain axis can exacerbate
various CNS disorders through aberrantly expressed metabolites such as short-chain fatty acids (…

Short‐chain fatty acids: microbial metabolites that alleviate stress‐induced brain–gut axis alterations

M Van de Wouw, M Boehme, JM Lyte… - The Journal of …, 2018 - Wiley Online Library
… microbes and their host, with short‐chain fatty acids (SCFAs) being perhaps the most studied.
… expression of the SCFA receptors free fatty acid receptors 2 and 3 remained unaffected by …

Neuropsychiatric Ramifications of COVID‐19: Short‐Chain Fatty Acid Deficiency and Disturbance of Microbiota‐Gut‐Brain Axis Signaling

EM Sajdel-Sulkowska - BioMed Research International, 2021 - Wiley Online Library
… SCFAs are also natural ligands for GPCRs and specifically identified receptors for free fatty
acids 2 and 3 (FFAR 2/3) found in many tissues, including the brain [48]. The deficiency of …

[HTML][HTML] High-fat diets containing different types of fatty acids modulate gut-brain axis in obese mice

Y Hua, J Shen, R Fan, R Xiao, W Ma - Nutrition & Metabolism, 2022 - Springer
fatty acids on gut–brain axis. In the present study, we examined the influence of different
dietary fatty acids on gut–brain axisacid diets exhibit on metabolic responses across gut–brain

Involvement of the gut-brain axis in vascular depression via tryptophan metabolism: a benefit of short chain fatty acids

W Xiao, J Li, X Gao, H Yang, J Su, R Weng, Y Gao… - Experimental …, 2022 - Elsevier
… vascular depression, but whether the gut-brain axis is involved remains unknown. In this
study, a rat … In conclusion, our data suggested the participation of the gut-brain axis in vascular …

Microbiota-derived short-chain fatty acids mediate the effects of dengzhan shengmai in ameliorating cerebral ischemia via the gut–brain axis

HH Guo, HR Shen, MZ Tang, N Sheng, X Ding… - Journal of …, 2023 - Elsevier
brain axis and the efficacy of DZSM in ameliorating cerebral ischemic diseases. … brain axis
comprises a bidirectional communication system via which gut microbes interact with the brain