… BM with normal aging affect all components and are specific to each brain region. These
changes are likely to have effects on local microvascular function that impact the normal …

… property that has the greatest effect on a substance's capacity to pierce the blood-brain …
substances have potent effects on brain function.) Once heroin has entered the brain, however, …

… Apical junctional complexes, notably tight junctions, are present in physiological barriers
constituted by a variety of epithelia and in brain endothelium forming the blood-brain-barrier (…

… Blood-brain barrier alterations have been reported in MDD, BD and SZ. Here, we provide
an overview of sex-specific immune, endocrine, vascular and transcriptional-mediated …

… The blood–brain barrier (BBB) is a dynamic platform for exchange of substances between
the blood and the brain parenchyma, and it is an essential functional gatekeeper for the …

… blood–brain barrier (BBB), enter the central nervous system (CNS), and cause neurocognitive
impairment. HIV-1-infected monocyte–macrophages traverse the BBB and enter the CNS …

… Two distinct blood–CNS barriers exist: the endothelial “blood–brain barrier” (BBB), … fluid
barrier,” situated at the choroid plexuses within the brain ventricular system, separating the brain …

… The blood brain barrier (BBB) is a specialized structure formed by brain endothelial cells (BECs)
that are tightly interconnected to form a boundary between the central nervous system (…

… The effects of the perivascular astrocyte on brain … of the key factors in inducing brain pathology
(Sharma, Chapter 15)… of the blood–brain and blood–spinal cord barriers following hyper…

… Based on these discussions, the emerging research needs, such as construction of the
new concept of blood–brain regional barriers, understanding of chemical effect on aged or …