Proinflammatory cytokines in serum of patients with acute cerebral ischemia: kinetics of secretion and relation to the extent of brain damage and outcome of disease

K Fassbender, S Rossol, T Kammer… - Journal of the …, 1994 - Elsevier
… In rcgard to the large dilution of IL-6 in peripheral blood, our results suggest a release of …
during the early phase of brain damage. The sourcc of the IL-6 remains unknown. Monoeytes …

Serum IL-6, IL-8 and IL-10 levels in multiple trauma compared to traumatic brain injury and combined trauma

A Seekamp, M van Griensven, U Lehmann… - … Journal of Trauma, 2002 - Springer
… In this study IL-6, IL-8 and IL-10 serum levels were measured in TBI patients, in MT patients
and in patients having sustained a combined injury. Initially, all three cytokine levels were …

[HTML][HTML] Serum IL-6: a candidate biomarker for intracranial pressure elevation following isolated traumatic brain injury

GW Hergenroeder, AN Moore, JP McCoy… - Journal of …, 2010 - Springer
… When blinded samples (n = 22) were assessed, a serum IL-6 cut-… of serum IL-6 were assessed
in patients with orthopedic injury (… Our results suggest that serum IL-6 can be used for the …

IL-10 levels in cerebrospinal fluid and serum of patients with severe traumatic brain injury: relationship to IL-6, TNF-α, TGF-β1 and blood–brain barrier function

E Csuka, MC Morganti-Kossmann… - Journal of …, 1999 - Elsevier
… of interleukin-10 (IL-… serum of 28 patients with severe traumatic brain injury (TBI) and
compared to control samples. The pattern of IL-10 was analyzed with respect to the patterns of IL-6, …

Correlation between serum IL-6 and CRP levels and severity of head injury in children

P Kalabalikis, K Papazoglou, D Gouriotis… - Intensive care …, 1999 - Springer
… processes including Alzheimer's disease, AIDS, multiple sclerosis, and Parkinson's
disease as well as acute brain injury in stroke and trauma [18, 21, 22]. If glia produced …

Early intrathecal production of interleukin-6 predicts the size of brain lesion in stroke

E Tarkowski, L Rosengren, C Blomstrand, C Wikkelsö… - Stroke, 1995 - Am Heart Assoc
IL-6 and the subsequent size of the brain lesion can be used as a prognostic tool, predicting
the size of the brain damage … of IL-1β in serum and significantly lower levels of IL-6 in serum

Production of cytokines following brain injury: beneficial and deleterious for the damaged tissue

MC Morganti-Kossman, PM Lenzlinger, V Hans… - Molecular …, 1997 - nature.com
… levels of serum IL-6. Interestingly, may contribute to deleterious secondary brain damage
IL-6 levels in CSF and serum correlated with each The kinetics of the release of cytokines …

Relations of serum high-sensitivity C-reactive protein and interleukin-6 levels with silent brain infarction

T Hoshi, K Kitagawa, H Yamagami, S Furukado… - Stroke, 2005 - Am Heart Assoc
… disease underlies such asymptomatic brain lesions. Although several … serum levels of
inflammatory markers, such as high-sensitivity C-reactive protein (hsCRP) and interleukin-6 (IL-6), …

IL-6 quotient (The ratio of cerebrospinal fluid IL-6 to serum IL-6) as a biomarker of an unruptured intracranial aneurysm

J Kamińska, V Dymicka-Piekarska… - Journal of …, 2021 - Taylor & Francis
… had a significantly higher IL-6 Quotient (CSF IL-6 concentration divided by serum IL-6
concentration) compared to patients without vascular lesions in the brain. A further detailed …

Association of serum IL-6 (interleukin 6) with functional outcome after intracerebral hemorrhage

AC Leasure, LR Kuohn, KN Vanent, MB Bevers… - Stroke, 2021 - Am Heart Assoc
IL-6 (interleukin 6) is a proinflammatory cytokine and an established biomarker in acute
brain injury. We sought to determine whether admission IL-6 levels are associated with severity …