[HTML][HTML] DNA methylation signatures within the human brain

C Ladd-Acosta, J Pevsner, S Sabunciyan… - The American Journal of …, 2007 - cell.com
… Aberrant DNA methylation of individual genes is a hallmark of cancer and … DNA methylation
might distinguish individual brain regions. We determined the quantitative DNA methylation

Alzheimer's disease: early alterations in brain DNA methylation at ANK1, BIN1, RHBDF2 and other loci

PL De Jager, G Srivastava, K Lunnon, J Burgess… - Nature …, 2014 - nature.com
brains to assess the methylation state of the brain's DNA in relation to Alzheimer's disease
(AD). We found that the level of methylation at … We validated 11 of the differentially methylated

Distinct DNA methylation changes highly correlated with chronological age in the human brain

DG Hernandez, MA Nalls, JR Gibbs… - Human molecular …, 2011 - academic.oup.com
… distinct brain regions, and furthermore, that the DNA methylation … of age on DNA methylation
status in human brain. We find that … between CpG methylation and aging of the human brain. …

Comprehensive DNA methylation and hydroxymethylation analysis in the human brain and its implication in mental disorders

T Kato, K Iwamoto - Neuropharmacology, 2014 - Elsevier
brains and performed comprehensive DNA methylation analyses using bead arrays of bisulfite
modified DNA and tiling array analysis of DNA … , and the DNA methylation status of bulk …

Neuronal activity modifies the DNA methylation landscape in the adult brain

JU Guo, DK Ma, H Mo, MP Ball, MH Jang… - Nature …, 2011 - nature.com
… To determine the extent to which neuronal activity modifies the landscape of neuronal
DNA methylation in vivo, we took a genome-wide approach to profile the DNA methylome of …

Targeting DNA methylation in the adult brain through diet

J Allison, A Kaliszewska, S Uceda, M Reiriz, N Arias - Nutrients, 2021 - mdpi.com
… signals in shaping brain DNA methylation during adulthood. We will … brain disorders [39] and
can influence DNA methylation in … the influence of gut microbiota on brain DNA methylation. …

Dynamic regulation of DNA methylation and brain functions

J Xie, L Xie, H Wei, XJ Li, L Lin - Biology, 2023 - mdpi.com
DNA cytosine methylation is a principal epigenetic … suggests that DNA methylation plays a
critical role in brain function… However, the mechanisms underlying aberrant DNA methylation

Reading the unique DNA methylation landscape of the brain: Non-CpG methylation, hydroxymethylation, and MeCP2

B Kinde, HW Gabel, CS Gilbert… - Proceedings of the …, 2015 - National Acad Sciences
… Here we discuss the distinct landscape of DNA methylation in neurons, how it is established…
of DNA methylation. We review studies of one critical reader of DNA methylation in the brain, …

BECon: a tool for interpreting DNA methylation findings from blood in the context of brain

RD Edgar, MJ Jones, MJ Meaney, G Turecki… - Translational …, 2017 - nature.com
… -based DNA methylation results in the context of brain tissue. We … brain regions and whole
blood, run on the Illumina 450 K Human Methylation Array to quantify the concordance of DNA

Evolution of DNA methylation in the human brain

H Jeong, I Mendizabal, S Berto, P Chatterjee… - Nature …, 2021 - nature.com
brain. Here we have elucidated DNA methylation changes during recent human brain
evolution… We demonstrate dynamic evolutionary trajectories of DNA methylation in cell-type and …