Brain interleukin 1 gene expression induced by peripheral lipopolysaccharide administration

E Ban, F Haour, R Lenstra - Cytokine, 1992 - Elsevier
peripheral administration with LPS. Another explanation may be that secondary effects of
LPS administration on IL-l receptor synthesis in brain … more likely that the brain IL-l receptor is …

Peripheral lipopolysaccharide administration transiently affects expression of brain-derived neurotrophic factor, corticotropin and proopiomelanocortin in mouse brain

S Schnydrig, L Korner, S Landweer, B Ernst… - Neuroscience …, 2007 - Elsevier
… ) expression and function. In the current study we administered a single, high dose of LPS (3
… changes in brain-derived neurotrophic factor (BDNF) gene expression within 1–6 days after …

Peripheral administration of lipopolysaccharide induces the expression of cytokine transcripts in the brain and pituitary of mice

S Layé, P Parnet, E Goujon, R Dantzer - Molecular brain research, 1994 - Elsevier
… an intraperitoneal injection of lipopolysaccharide (LPS, 10 /~g/mouse). The kinetics of
cytokine gene expression induced by peripheral LPS in the pituitary and brain structures were …

Peripheral administration of lipopolysaccharide induces activation of microglial cells in rat brain

M Buttini, S Limonta, H Boddeke - Neurochemistry international, 1996 - Elsevier
peripheral LPS treatment are, just as in the case of LPS-… that peripheral, intravenous
administration of LPS produces a strong … the rat brain. The functional consequences induced in the …

Pro-inflammatory and anti-inflammatory cytokine mRNA induction in the periphery and brain following intraperitoneal administration of bacterial lipopolysaccharide

NP Turrin, D Gayle, SE Ilyin, MC Flynn… - Brain research …, 2001 - Elsevier
brain. In this study, we investigated cytokine and neuropeptide mRNA profiles in specific brain
regions and peripheral … response to the intraperitoneal administration of LPS. For the first …

Effects of peripheral administration of LPS on the expression of immunoreactive interleukin‐1α, β, and receptor antagonist in rat brain

AM VAN DAM, S Poole… - Annals of the New …, 1998 - Wiley Online Library
… We raised the question whether endogenous production of the cytokine IL-1 in the brain is
induced by peripheral administration of LPS and thus may contribute to the induction of brain-…

How does peripheral lipopolysaccharide induce gene expression in the brain of rats?

AK Singh, Y Jiang - Toxicology, 2004 - Elsevier
… This study showed that peripheral LPS caused several folds increase in the brain uptake
of [ 14 C ]sucrose but did not affect the uptake of [ 14 C ]dextran. Thus, LPS transiently opens …

Induction of pro-inflammatory cytokine mRNAs in the brain after peripheral injection of subseptic doses of lipopolysaccharide in the rat

N Quan, EL Stern, MB Whiteside… - Journal of …, 1999 - Elsevier
… Induction of inhibitory factor κBα mRNA in the central nervous system after peripheral
lipopolysaccharide administration: an in situ hybridization histochemistry study in the rat …

Time course and localization patterns of interleukin-1β messenger RNA expression in brain and pituitary after peripheral administration of lipopolysaccharide

N Quan, M Whiteside, M Herkenham - Neuroscience, 1998 - Elsevier
… is primarily expressed by non-neuronal cells of the brain in the brain parenchyma. … brain
IL-1 activity after peripheral lipopolysaccharide injection derives from cells of the blood brain

Cyclooxygenase 2 mRNA expression in rat brain after peripheral injection of lipopolysaccharide

N Quan, M Whiteside, M Herkenham - Brain research, 1998 - Elsevier
… in the brain following peripheral LPS administration, COX 2 mRNA expression was examined
… intraperitoneally (ip) or intravenously (iv) with various doses of LPS or saline. Constitutive …