Structure and function of adenosine receptors and their genes
BB Fredholm, G Arslan, L Halldner, B Kull… - Naunyn-Schmiedeberg's …, 2000 - Springer
… Fredholm BB, Lindgren E, Lindström K, Nordstedt C (1987b) Adrenoceptor stimulation, but
not muscarinic stimulation, increases cyclic AMP accumulation in brain slices due to protein …
not muscarinic stimulation, increases cyclic AMP accumulation in brain slices due to protein …
[HTML][HTML] Adenosine receptors as drug targets—what are the challenges?
JF Chen, HK Eltzschig, BB Fredholm - Nature reviews Drug discovery, 2013 - nature.com
… The A 1 receptor is the most conserved adenosine receptor subtype among species 23 ,
and it is widely expressed throughout the body with the highest levels found in the brain, …
and it is widely expressed throughout the body with the highest levels found in the brain, …
A2a adenosine receptor gene expression in developing rat brain
DR Weaver - Molecular brain research, 1993 - Elsevier
… A2a adenosine receptor genem the strlatum and ~ts transient expression elsewhere m …
brain and cerebral vasculature If the A2a adenosine receptor mRNA is translated into receptor …
brain and cerebral vasculature If the A2a adenosine receptor mRNA is translated into receptor …
Distribution of adenosine receptors in the postmortem human brain: an extended autoradiographic study
P Svenningsson, H Hall, G Sedvall, BB Fredholm - Synapse, 1997 - Wiley Online Library
… The data in this study confirm that the distribution of adenosine A1 receptors in human
brain differs from that in several experimental animals (Fastbom et al., 1987b). Although the …
brain differs from that in several experimental animals (Fastbom et al., 1987b). Although the …
[HTML][HTML] Why target brain adenosine receptors? A historical perspective
BB Fredholm, P Svenningsson - Parkinsonism & Related Disorders, 2020 - Elsevier
… “brain adenosine receptors”. Interest in adenosine as a significant modulator of brain function
… ,5′ -cyclic adenosine monophosphate (cAMP) in brain slices decreased when they added …
… ,5′ -cyclic adenosine monophosphate (cAMP) in brain slices decreased when they added …
[HTML][HTML] Adenosine receptor containing oligomers: their role in the control of dopamine and glutamate neurotransmission in the brain
… adenosine receptor-containing oligomers may allow not only the control of the adenosinergic
function … significant developments based on adenosine receptor oligomerization that are …
function … significant developments based on adenosine receptor oligomerization that are …
Caffeine and adenosine
JA Ribeiro, AM Sebastiao - Journal of Alzheimer's disease, 2010 - content.iospress.com
… adenosine receptors and on the mechanisms they operate in order to infer how caffeine exerts
most of its actions in the brain… actions are mediated by adenosine receptors. These studies…
most of its actions in the brain… actions are mediated by adenosine receptors. These studies…
Association of adenosine receptor gene polymorphisms and in vivo adenosine A1 receptor binding in the human brain
C Hohoff, V Garibotto, D Elmenhorst, A Baffa… - …, 2014 - nature.com
… The main finding of the present study is an association of SNPs of adenosine receptor
genes with in vivo [ 18 F]CPFPX binding to the A 1 AR in brains of healthy human subjects, an …
genes with in vivo [ 18 F]CPFPX binding to the A 1 AR in brains of healthy human subjects, an …
Adenosine and related drugs in brain diseases: present and future in clinical trials
LV Lopes, AM Sebastiao… - Current topics in …, 2011 - ingentaconnect.com
… of adenosine or adenosine receptor ligands as therapeutic agents in several brain disorders.
… This is particularly the case in the brain, where adenosine receptors are highly expressed, …
… This is particularly the case in the brain, where adenosine receptors are highly expressed, …
Adenosine role in brain functions: pathophysiological influence on Parkinson's disease and other brain disorders
AM Soliman, AM Fathalla, AA Moustafa - Pharmacological Reports, 2018 - Elsevier
… Through the activation of purinoceptors (P 1 ) and/or adenosine receptors, adenosine
modulates the release of various neurotransmitters including acetylcholine, glutamate, γ-…
modulates the release of various neurotransmitters including acetylcholine, glutamate, γ-…