Metabolism and functions of glutathione in brain

R Dringen - Progress in neurobiology, 2000 - Elsevier
glutathione metabolism of different brain cell types in culture. The glutathione content of brain
Glutathione levels in cultured astroglial cells can be modulated by a variety of treatments (…

Glutathione pathways in the brain

R Dringen, J Hirrlinger - 2003 - degruyter.com
Glutathione metabolism in brain metabolic interaction between astrocytes and neurons in …
Effect of orally administered glutathione on glutathione levels in some organs of rats: role of …

Glutathione in the Brain

K Aoyama - International journal of molecular sciences, 2021 - mdpi.com
levels in the brain, where the regulatory system for GSH synthesis is independent of that
in peripheral tissues. Therefore, the molecular mechanisms underlying GSH dysfunction in …

Low glutathione levels in brain regions of aged rats

V Ravindranath, BR Shivakumar… - Neuroscience …, 1989 - Elsevier
Glutathione (GSH) was measured in 6 regions of brain and liver of young adult, middle-aged
and aged rats. GSH levels … significantly in all the regions of brain examined and in the liver …

Brain glutathione levels–a novel biomarker for mild cognitive impairment and Alzheimer's disease

PK Mandal, S Saharan, M Tripathi, G Murari - Biological psychiatry, 2015 - Elsevier
… result of low brain GSH … brain GSH levels were reduced in AD as compared with healthy
young subjects (27). In this study, we aimed to probe the association between brain GSH levels

Do glutathione levels decline in aging human brain?

J Tong, PS Fitzmaurice, A Moszczynska… - Free Radical Biology …, 2016 - Elsevier
… with glutathione deficiency in human brain. We measured reduced glutathione (GSH) levels
in multiple regions of autopsied brain of normal subjects (n=74) aged one day to 99 years. …

Alzheimer's and Parkinson's disease: brain levels of glutathione, glutathione disulfide, and vitamin E

JD Adams, LK Klaidman, IN Odunze, HC Shen… - Molecular and Chemical …, 1991 - Springer
… extracts of fresh brain tissue to inhibit postmortem changes in vitamin E. Our previously
reported mouse brain vitamin E levels are similar to reported rat brain vitamin E levels, where rats …

Glutathione in brain disorders and aging

IY Iskusnykh, AA Zakharova, D Pathak - Molecules, 2022 - mdpi.com
… Impairment of glutathione function in the brain is linked to loss … through which glutathione
regulates brain metabolism are … signaling cascades that regulate glutathione in neurons and …

Decreased levels of glutathione, the major brain antioxidant, in post-mortem prefrontal cortex from patients with psychiatric disorders

JW Gawryluk, JF Wang, AC Andreazza… - International Journal …, 2011 - academic.oup.com
… enzyme levels in MDD and BD. Thus, in this study we examined the GSH antioxidant system
in post-mortem brain from patients with MDD, BD, and SCZ, and report diminished levels of …

Brain glutathione levels in patients with epilepsy measured by in vivo 1H-MRS

SG Mueller, AH Trabesinger, P Boesiger, HG Wieser - Neurology, 2001 - AAN Enterprises
brain, the reported levels for glutathione for humans range from 0.8 to 3.1 mM depending on
the brain … , we measured the in vivo brain GSH levels in 19 patients with focal epilepsy with …