… protect neuronal integrity, adenosine might also aggravate neuronal … adenosine receptor
function in the brain immune system should help develop novel therapeutic ways to treat brain …

… outline evidence that adenosine receptor (AR) activation can modulate blood–brain barrier
(… Barriers of the central nervous system (CNS) constitute a protective and regulatory interface …

… some of the adenosine receptors (A1, A2A, A2B, and A3; rectangles). In terms of intracellular
metabolism of adenosine, all cell types and compartments can convert ATP into adenosine …

… correspondingly dampens the immune system, where the … sion of TCR in regulatory T cells
suppress immune response, … effects of adenosine receptor agonists on cerebral blood flow …

… In order to characterize the nature of this putative adenosine receptor, we investigated the
influence of selected adenosine receptor … subtypes are similar to those described in brain. 76 …

… Schematic representation of the main functions mediated by adenosine receptors on
immune cells. Abbreviations: ADA adenosine deaminase, COX-2 cyclooxygenase-2, ERK-1/2 …

… constituents of the innate and adaptive immune systems. Finally, we discuss the therapeutic
basis of harnessing the adenosine receptor system in managing patients suffering from …

… Adenosine receptor dysfunction is also involved in the pathology … , the adenosine receptor
balance theory is important for brain … Researchers also found that the c-fos immune response …

… of adenosine receptors, could have a role in the onset or the development of central nervous
system … ADA1 plays a crucial role in adaptive immune system development and exhibits an …

… blood–brain barrier, it can act as a signaling molecule between the periphery and the brain.
… A3) cell surface G protein-coupled adenosine receptors (ARs) that are expressed in some …