[HTML][HTML] Electrocorticography reveals thalamic control of cortical dynamics following traumatic brain injury

S Mofakham, A Fry, J Adachi, PL Stefancin… - Communications …, 2021 - nature.com
… Moreover, in our model, thalamic input … the thalamic input was reduced. We suggest that
simple and repetitive cortical dynamics associated with the coma attractor (when thalamic input

[HTML][HTML] Reorganization of thalamic inputs to lesioned cortex following experimental traumatic brain injury

XE Ndode-Ekane, MM Puigferrat Pérez… - International Journal of …, 2021 - mdpi.com
brain area most affected by traumatic brain injury (TBI) [1]. The ensuing cortical lesion ultimately
leads to alterations in brain … , mostly attributed to diffuse axonal injury and the less known …

[HTML][HTML] Injury to thalamocortical projections following traumatic brain injury results in attractor dynamics for cortical networks

S Mofakham, Y Liu, A Hensley, JR Saadon… - Progress in …, 2022 - Elsevier
… Therefore, we hypothesized that lack of thalamic input strongly constrains the flexibility of
the cortex, and only allows it to adopt a small number of possible states. This hypothesis leads …

Thalamic and extrathalamic mechanisms of consciousness after severe brain injury

ES Lutkenhoff, J Chiang, L Tshibanda… - Annals of …, 2015 - Wiley Online Library
… that “while thalamus might be crucial for transmitting specific information that provides the
content of the waking state, and may therefore contribute to overall arousal if thalamic input

Central thalamic contributions to arousal regulation and neurological disorders of consciousness

ND Schiff - Annals of the New York Academy of Sciences, 2008 - Wiley Online Library
thalamus may lead to rational therapeutic approaches to the treatment of impaired arousal
regulation following nonprogressive brain injuriesinputs from the specific thalamic inputs to …

Central thalamic deep‐brain stimulation in the severely injured brain: rationale and proposed mechanisms of action

ND Schiff - Annals of the New York Academy of Sciences, 2009 - Wiley Online Library
… The reduction of input to the central thalamus may play a key role … brain injury or more than
a year after traumatic brain injury typically show overwhelming neuronal death in the thalamus

Central thalamic deep brain stimulation to support anterior forebrain mesocircuit function in the severely injured brain

ND Schiff - Journal of Neural Transmission, 2016 - Springer
… , which is expected to produce sufficient loss of afferent input to the medium spiny neurons
(MSNs) … in the central thalamus of a patient with severe traumatic brain injury. Figure elements …

Behavioural improvements with thalamic stimulation after severe traumatic brain injury

ND Schiff, JT Giacino, K Kalmar, JD Victor, K Baker… - Nature, 2007 - nature.com
brain injury typically results in en passant injuries to thalamic … We sought to determine whether
DBS in the central thalamus … brainstem inputs, which adjust firing rates in central thalamic

Hyper-connectivity of the thalamus during early stages following mild traumatic brain injury

C Sours, EO George, J Zhuo, S Roys… - Brain imaging and …, 2015 - Springer
… Furthermore, an understanding of heightened sensitivity to sensory related inputs during
early stages of injury may facilitate enhanced prediction of safe return to work. …

Thalamic nuclei after human blunt head injury

WL Maxwell, MA MacKinnon, DH Smith… - … of Neuropathology & …, 2006 - academic.oup.com
… After traumatic brain injury (TBI), there is impairment of cognitive and memory functions in
both … Loss of cortical input following loss of thalamic neurons may provide a structural basis for …