Brain lesions in septic shock: a magnetic resonance imaging study

T Sharshar, R Carlier, F Bernard, C Guidoux… - Intensive care …, 2007 - Springer
… to accumulate in the brain and then to contribute to brain dysfunction [6, 10]. The
leucoencephalopathy observed in septic shock in this study, mimicked white matter lesions reported …

Pattern of brain injury in the acute setting of human septic shock

A Polito, F Eischwald, ALL Maho, A Polito, E Azabou… - Critical care, 2013 - Springer
Sepsis-associated brain dysfunction has been linked to white matter lesions (leukoencephalopathy) …
Our objective was to assess the prevalence of brain lesions in septic shock patients …

Incidence and pattern of brain lesions in paediatric septic shock patients

D Sanz, F D'Arco, CA Robles… - The British Journal of …, 2018 - academic.oup.com
… The incidence of acute brain lesion in our septic shock cohort was 10% (20 of 193). … The
total incidence of acute brain lesion in our septic shock cohort was 10.3% (20 of 193). Results …

The neuropathology of septic shock

T Sharshar, D Annane, GL de la Gradmaison… - Brain …, 2004 - Wiley Online Library
… 23 patients who died from septic shock, 8 from non-septic shock, and 5 controls … brain
lesions characteristic of septic shock and to consider their possible role in the causation of “septic

Neuropathology of septic shock

F Gray, T Sharshar… - Neuropathology and …, 2002 - Wiley Online Library
lesions (PVL) and deep subcortical lesions (DWML) demonstrated in MRI scans of fixed coronal
brain slices, from elderly postmortem brain … from the same brains. Immunohistochemistry …

Elevated serum levels of S-100β protein and neuron-specific enolase are associated with brain injury in patients with severe sepsis and septic shock

DN Nguyen, H Spapen, F Su, J Schiettecatte… - Critical care …, 2006 - journals.lww.com
… Histologic brain injury is detected early after the induction of sepsis in various animal …
brain lesions are described in autopsied patients who died of sepsis and septic shock ( 5, 6 )…

Brain damage complicating septic shock: acute haemorrhagic leucoencephalitis as a complication of the generalised Shwartzman reaction.

DI Graham, PO Behan, IA More - Journal of Neurology, Neurosurgery …, 1979 - jnnp.bmj.com
… "septic shock" caused by Gram-negative septicaemia are described. The changes in the
brains were … is the final common pathway that produces tissue damage in the brain and kidney. …

Understanding brain dysfunction in sepsis

R Sonneville, F Verdonk, C Rauturier, IF Klein… - Annals of intensive …, 2013 - Springer
Brain lesions in septic shock have been described in areas of the brain susceptible to
ischemia (including Ammon’s horn, the frontal junctional cortex, the lenticular nuclei, the dentate …

Postmortem evidence of brain inflammatory markers and injury in septic patients: a systematic review

T Barichello, JS Generoso, D Dominguini… - Critical care …, 2022 - journals.lww.com
… The Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3)
demarcated sepsis as life-threatening organ dysfunction caused by a dysregulated host response …

Neuroimaging findings in sepsis-induced brain dysfunction: association with clinical and laboratory findings

G Orhun, F Esen, PE Özcan, S Sencer, B Bilgiç… - Neurocritical Care, 2019 - Springer
… Among 493 sepsis and septic shock patients, who … brain lesions and another 16% displayed
brain atrophy falling within the previously reported prevalence range. Thus, the brain lesion