Efficacy of epidermal growth factor receptor tyrosine kinase inhibitors for brain metastasis in non-small cell lung cancer patients harboring either exon 19 or 21 …
SJ Park, HT Kim, DH Lee, KP Kim, SW Kim, C Suh… - Lung cancer, 2012 - Elsevier
… They received either erlotinib or gefitinib once a day. Out of total 28 patients enrolled, 23 …
therapy for metastatic brain tumors during their disease course, either whole brain radiotherapy …
therapy for metastatic brain tumors during their disease course, either whole brain radiotherapy …
Efficacy of epidermal growth factor receptor tyrosine kinase inhibitors for brain metastasis in non-small cell lung cancer patients harboring either exon 19 or 21 …
K Kim, DH Lee, J Lee, C Suh, S Kim, JC Lee… - Journal of Clinical …, 2011 - ascopubs.org
… and 2 patients whole brain radiation. Conclusions: EGFR TKI were effective in NSCLC
patients with brain metastasis harboring either exon 19 or 21 mutations. Exon 19 mutations were …
patients with brain metastasis harboring either exon 19 or 21 mutations. Exon 19 mutations were …
[HTML][HTML] Prognostic analysis of patients with non-small cell lung cancer harboring exon 19 or 21 mutation in the epidermal growth factor gene and brain metastases
J Wang, Z Liu, Q Pang, T Zhang, X Chen, P Er, Y Wang… - BMC cancer, 2020 - Springer
… benefits for patients with NSCLC and brain metastases. The role of radiotherapy in the … of
intracranial lesions and prolonging the survival than either therapy alone. The benefits seemed …
intracranial lesions and prolonging the survival than either therapy alone. The benefits seemed …
Exon 19 deletion of epidermal growth factor receptor is associated with prolonged survival in brain metastases from non-small-cell lung cancer
H Li, X Zhang, J Cao, P Su, J Lian, X Song, W Yang… - Tumor Biology, 2015 - Springer
… However, in our study, treatment method contributed to statistically significant differences
in overall survival of patients with either EGFR exon 19 deletion or 21 point mutation. One of …
in overall survival of patients with either EGFR exon 19 deletion or 21 point mutation. One of …
EGFR mutated non-small cell lung cancer patients: more prone to development of bone and brain metastases?
LEL Hendriks, EF Smit, BAH Vosse, WW Mellema… - Lung cancer, 2014 - Elsevier
… from mNSCLC diagnosis to metastatic bone disease and 1st SRE did not differ either. Post
… 3 EGFR+ patients had an exon 18 mutation and 8 had an exon 20 mutation; these patients …
… 3 EGFR+ patients had an exon 18 mutation and 8 had an exon 20 mutation; these patients …
[HTML][HTML] Exon 20 YVMA insertion is associated with high incidence of brain metastasis and inferior outcome of chemotherapy in advanced non-small cell lung cancer …
S Yang, Y Wang, C Zhao, X Li, Q Liu… - … lung cancer research, 2021 - ncbi.nlm.nih.gov
… incidence of baseline extrathoracic metastasis (P= 0.009), notably brain metastasis (P= …
brain metastasis (P= 0.002) compared by Gray’s test, with estimated 12-month brain metastasis …
brain metastasis (P= 0.002) compared by Gray’s test, with estimated 12-month brain metastasis …
… associated with increased brain metastasis risk in non–small cell lung cancer: Comprehensive genomic profiling of 61 resected brain metastases versus primary non …
H Wang, Q Ou, D Li, T Qin, H Bao, X Hou, K Wang… - Cancer, 2019 - Wiley Online Library
… cases (in either primary lung tumors or brain metastases) are … NSCLC and matched brain
metastases are indicated by dots … (n = 25), 56% carried exon 19 deletion mutations, and L858R …
metastases are indicated by dots … (n = 25), 56% carried exon 19 deletion mutations, and L858R …
CNS Metastases in Patients With MET Exon 14–Altered Lung Cancers and Outcomes With Crizotinib
… the probability of developing brain metastasis in the 83 patients with MET exon 14–altered …
which are selective type Ib MET TKIs, are either approved or currently under study in the clinic…
which are selective type Ib MET TKIs, are either approved or currently under study in the clinic…
[HTML][HTML] Frequent genetic alterations in EGFR-and HER2-driven pathways in breast cancer brain metastases
I Hohensee, K Lamszus, S Riethdorf… - The American journal of …, 2013 - Elsevier
… for developing brain metastases, represented by genetic alterations in either HER2 or EGFR/…
for mutations using either cDNA as template (covering exons 6 to 10 and exons 19 to 20) or …
for mutations using either cDNA as template (covering exons 6 to 10 and exons 19 to 20) or …
[HTML][HTML] Relevance of PTEN loss in brain metastasis formation in breast cancer patients
H Wikman, K Lamszus, N Detels, L Uslar… - Breast Cancer …, 2012 - Springer
… In addition, 10 samples were used to sequence exons 3 and 5 for mutations. … exon 4. In
the second tumor, both alleles were mutated, resulting in one product with a deletion of exons 4 …
the second tumor, both alleles were mutated, resulting in one product with a deletion of exons 4 …
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- lung cancer brain metastasis
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- brain metastases exon 19 deletion
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- egfr mutation status brain metastasis
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- comparison of the efficacies brain metastasis
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- role of egfr mutation brain metastasis
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- prognostic factor brain metastasis