Pathogenesis of hepatic encephalopathy
D Häussinger, F Schliess… - … of Gastroenterology and …, 2002 - Wiley Online Library
… brain osmolytes after portacaval anastomosis in the rat: implications for ammonia-induced
brain … gold standard for diagnosis of clinical and subclinical hepatic encephalopathy. Dig. Dis. …
brain … gold standard for diagnosis of clinical and subclinical hepatic encephalopathy. Dig. Dis. …
Brain edema and hepatic encephalopathy
J Cordoba, AT Blei - Seminars in liver disease, 1996 - thieme-connect.com
… osmolytes) in the brain, whose main role was to protect the cells from the hyperosmolar effects
of hyperglycemia. If blood glucose is rapidly corrected, the exit of these organic osmolytes …
of hyperglycemia. If blood glucose is rapidly corrected, the exit of these organic osmolytes …
Osmotic shifts, cerebral edema, and neurologic deterioration in severe hepatic encephalopathy
EM Liotta, AL Romanova, BD Lizza… - Critical care …, 2018 - journals.lww.com
… Hepatic encephalopathy (HE)—liver disease-related brain … to morbidity and mortality in
liver disease ( 1–4 ). During … in nonsodium osmolytes, thereby lessening cerebral edema. …
liver disease ( 1–4 ). During … in nonsodium osmolytes, thereby lessening cerebral edema. …
[PDF][PDF] Effects of dilutional hyponatremia on brain organic osmolytes and water content in patients with cirrhosis
T Restuccia, B Gómez‐Ansón, M Guevara… - …, 2004 - Wiley Online Library
… brain organic osmolytes and brain water content in cirrhosis. … The remarkable changes
in brain organic osmolytes may … link between hyponatremia and hepatic encephalopathy. …
in brain organic osmolytes may … link between hyponatremia and hepatic encephalopathy. …
[PDF][PDF] Plasmatic osmolality and hepatic encephalopathy: A new player on the field?
… Cerebral oedema is a result of brain hypertonicity and increasing non-permeable
molecules … of energy metabolism in overt hepatic encephalopathy. J Hepatol. 2016;65:1120-1130. …
molecules … of energy metabolism in overt hepatic encephalopathy. J Hepatol. 2016;65:1120-1130. …
Glucose-derived osmolytes and energy impairment in brain edema accompanying liver failure: the role of glutamine reevaluated
J Albrecht - Gastroenterology, 2003 - gastrojournal.org
… In ammonium acetate-infused rats, advancement of HE from a pre-coma stage to coma
correlated with increased brain ammonia under conditions when glutamine synthesis was …
correlated with increased brain ammonia under conditions when glutamine synthesis was …
Organic osmolytes in hyponatremia and ammonia toxicity
J Heins, C Zwingmann - Metabolic brain disease, 2010 - Springer
… the pathogenesis of hepatic encephalopathy and hyponatremia. … The role of brain glutamine
and organic osmolytes in … The observations that the decrease of brain organic osmolytes in …
and organic osmolytes in … The observations that the decrease of brain organic osmolytes in …
Osmotic and oxidative/nitrosative stress in ammonia toxicity and hepatic encephalopathy
B Görg, F Schliess, D Häussinger - Archives of biochemistry and biophysics, 2013 - Elsevier
… Here, increased brain glutamine levels are accompanied by decreased brain myo-inositol
and taurine levels but, importantly, the overall content of the brain osmolytes determined in …
and taurine levels but, importantly, the overall content of the brain osmolytes determined in …
[HTML][HTML] Brain edema in acute liver failure. A window to the pathogenesis of hepatic encephalopathy
J Vaquero, C Chung, AT Blei - Annals of hepatology, 2003 - Elsevier
… the levels of brain organic osmolytes. Infusion of ammonia … osmolytes in both normonatremic
and hyponatremic rats. Importantly, infusion of ammonia resulted in a higher degree of brain …
and hyponatremic rats. Importantly, infusion of ammonia resulted in a higher degree of brain …
Selective alterations of brain osmolytes in acute liver failure: protective effect of mild hypothermia
C Zwingmann, N Chatauret, C Rose, D Leibfritz… - Brain research, 2004 - Elsevier
… effects of ALF due to hepatic devascularization on the concentrations of brain glutamine
and other osmolytes in relation to the severity of encephalopathy and brain edema. In addition, …
and other osmolytes in relation to the severity of encephalopathy and brain edema. In addition, …
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