Markers for human brain pericytes and smooth muscle cells

LCD Smyth, J Rustenhoven, EL Scotter… - Journal of chemical …, 2018 - Elsevier
Brain pericytes and vascular smooth muscle cells (vSMCs) are a critical component … cerebral
blood flow and blood-brain barrier integrity. Identification of subtypes of mural cells in tissue

Neuroectodermal origin of brain pericytes and vascular smooth muscle cells

J Korn, B Christ, H Kurz - Journal of Comparative Neurology, 2002 - Wiley Online Library
… The origin of vascular pericytes (PCs) and smooth muscle cells (vSMCs) in the brain has …
We transplanted complete halves of brain anlagen, or dorsal (presumptive neural crest [NC]…

Induction of alpha-smooth muscle actin expression in cultured human brain pericytes by transforming growth factor-beta 1.

MM Verbeek, I Otte-Höller, P Wesseling… - The American journal …, 1994 - ncbi.nlm.nih.gov
… human brain pericytes (HBPs) as a model system of pericyte activation. The cells were …
On the other hand, our results show that smooth muscle cells in vitro are FXIIIpositive. This …

[HTML][HTML] Regional blood flow in the normal and ischemic brain is controlled by arteriolar smooth muscle cell contractility and not by capillary pericytes

RA Hill, L Tong, P Yuan, S Murikinati, S Gupta… - Neuron, 2015 - cell.com
Pericytes in brain capillaries completely lack expression of smooth muscle actin (SMA),
consistent with our finding that only microvessels enveloped by mural cells with a circumferential …

[HTML][HTML] Isolation and differential transcriptome of vascular smooth muscle cells and mid-capillary pericytes from the rat brain

S Chasseigneaux, Y Moraca, V Cochois-Guégan… - Scientific reports, 2018 - nature.com
… -brain barrier and regulation of the cerebral blood … smooth muscle cells (VSMCs) and
mid-capillary pericytes (mcPCs), which differ among others by their expression of smooth muscle

[HTML][HTML] Regional early and progressive loss of brain pericytes but not vascular smooth muscle cells in adult mice with disrupted platelet-derived growth factor receptor …

AM Nikolakopoulou, Z Zhao, A Montagne… - PLoS One, 2017 - journals.plos.org
… have contributed to better understanding of the role of pericytes in the brain. Here, we …
causing loss of pericytes and vascular smooth muscle cells (VSMCs) in the developing brain. We …

Alpha-smooth muscle actin, a differentiation marker of smooth muscle cells, is present in microfilamentous bundles of pericytes.

O Skalli, MF Pelte, MC Peclet… - … of Histochemistry & …, 1989 - journals.sagepub.com
… alpha-Smooth muscle (alpha-sm) actin, an isoform typical of smooth muscle cells (SMC)
and present in high amounts in vascular SMC, was demonstrated in the cytoplasm of pericytes

Brain pericytes: emerging concepts and functional roles in brain homeostasis

M Kamouchi, T Ago, T Kitazono - Cellular and molecular neurobiology, 2011 - Springer
Pericytes share cell markers with smooth muscle cells and with mesenchymal stem …
cells toward the smooth muscle cell/pericyte lineage with changes in phenotype- and cell-specific …

Differential expression of α‐actin mRNA and immunoreactive protein in brain microvascular pericytes and smooth muscle cells

RJ Boado, WM Pardridge - Journal of neuroscience research, 1994 - Wiley Online Library
cells or in pericytes. In conclusion, the a-actin mRNA is expressed in brain microvascular
pericytes in tissue … protein is not expressed in brain microvascular pericytes in vivo. These data …

The versatility of microvascular pericytes: from mesenchyme to smooth muscle?

V Nehls, D Drenckhahn - Histochemistry, 1993 - Springer
… tion that brain pericytes might represent a unique cell population which differs … smooth
muscle cells. It seems likely that similar transitions of midcapillary pericytes to smooth muscle cells