Characterization of the brain proteome of rats with diabetes mellitus through two-dimensional electrophoresis and mass spectrometry

D Karthik, S Ravikumar - Brain research, 2011 - Elsevier
… a comprehensive proteomic analysis for comparison of rat brain proteome by using advance
… type 1 diabetic rats and C. dactylon-treated diabetic rats at 2 weeks following diabetes onset…

Proteome analysis of differential protein expression in brain of rats with type 1 diabetes mellitus

X Li, W Pan, GZ Yang, YN Di, F Zhao… - … & diabetes, 2011 - thieme-connect.com
… : Proteomic approach was applied to identify differential protein expressed in brain of rats with
type 1 diabetes mellitus … potential biomarkers for pathological changes of brain with T1DM. …

Mitochondrial proteome analysis reveals depression of the Ndufs3 subunit and activity of complex I in diabetic rat brain

F Taurino, E Stanca, L Siculella, R Trentadue… - … of proteomics, 2012 - Elsevier
Proteomic analysis in dorsal root-ganglia of STZ diabetic rats has, however, shown a … The
results of the present proteomic analysis of brain mitochondria of the STZ diabetic rats, in the …

Influence of sex, age and diabetes on brain transcriptome and proteome modifications following cerebral ischemia

L Ramiro, J Faura, A Simats, P García-Rodríguez… - BMC neuroscience, 2023 - Springer
… is rapidly induced in the ischemic core in a rat model of focal cerebral ischemia [56, 57]. … ,
hyperlipoproteinemia, and diabetes mellitus considerably alter hemopoietic processes [86]. In …

Proteomics approaches to understand linkage between Alzheimer's disease and type 2 diabetes mellitus

Z Mirza, A Ali, G Md Ashraf, MA Kamal… - CNS & Neurological …, 2014 - ingentaconnect.com
… profiles have been analysed from rats with streptozotocin-induced diabetes and normal
rats [34]. In … in body fluids that are both related to brain proteome changes and are AD-specific. …

Proteomics of the rat myocardium during development of type 2 diabetes mellitus reveals progressive alterations in major metabolic pathways

AV Edhager, JA Povlsen, B Løfgren… - Journal of Proteome …, 2018 - ACS Publications
proteome alterations in myocardial tissue from ZDF-rats during development of T2DM, we
employed quantitative proteomics using … Male ZDF rats with homozygous mutation in the leptin …

Proteomic changes associated with diabetes in the BB-DP rat

DT Johnson, RA Harris, S French… - … Endocrinology and …, 2009 - journals.physiology.org
… With regard to urea synthesis, a 70% increase in urea synthetic rate has been reported in a
rat model of diabetes (3, 60) as well as in human insulin-dependent diabetes mellitus (2) that …

Alzheimer's disease and type 2 diabetes mellitus: A systematic review of proteomic studies

J Diniz Pereira, V Gomes Fraga… - Journal of …, 2021 - Wiley Online Library
… the proteomic profile in diabetic patients with AD. Therefore, this study aimed to systematically
review the studies using proteomic … applied the proteomic methodology in brain tissue or …

[HTML][HTML] … proteomic alterations in brain mitochondria-associated ER membranes caused by chronic psychological stress exposure: Implications for cognitive decline in …

H Xu, W Zhou, L Zhan, H Sui, L Zhang, C Zhao… - Aging (Albany …, 2020 - ncbi.nlm.nih.gov
rat brains, three independent methods were used. First, the different steps of MAM preparation
from ZDF rat brains … and 12 are associated with diabetes mellitus. Finally, according to the …

Hippocampal proteins discovery of diabetes-induced central neuropathy based on proteomics

Y Zhao, S Huan, Y Yang, W Gao, J Wang - NeuroReport, 2022 - journals.lww.com
… Because chronic hyperglycemia results in neurodegenerative diseases, brain aging, brain
… Therefore, we hypothesized that the hippocampus of diabetic rats might exhibit central …