1 天前 - … Diffuse Intrinsic Pontine Glioma (DIPG) is a universally fatal pediatric brain cancer
… Taken together, our study finds that the methylome of DIPG is highly disordered but is …

1 天前 - … brain controls, and 1 hindbrain neural stem cell control, and applied a novel analytic
pipeline (InformME) to generate DNA … We identified key genes and regulatory regions with …

13 天前 - … To enhance our understanding 26 of how DNA methylation is implicated in regulation
… brains, here we present their first genome-wide, single-base- 28 resolution methylomes …

15 天前 - … the DNA methylome to … in DNA 404 methylation in both heterozygous and
homozygous mutant cells, is an important step to 405 illuminate mechanisms behind abnormal brain …

22 天前 - … We used a mouse model carrying extra SNCA to examine its consequences on
gene expression and DNA methylation during midlife in a brain region linked to many PD …

31 天前 - … of smoking were run across five brain regions for 14 individuals using DNAm from
the … discrimination of smoking status in both blood and brain, but these loci did not overlap …

72 天前 - … tau protein are accumulated in the brain tissue [14]. … methylomes from blood
samples of twins discordant for Alzheimer’s disease. In Publication IV we analyze the methylomes …

77 天前 - … The epigenetic landscape of the human brain undergoes a … DNA methylation sites
when compared to other techniques while offering a comprehensive view of methylomes and …

141 天前 - … methylome sequencing of genomic DNA extracted from whole blood using bisulfite
sequencing services at Psomagen with ~20X coverage. Differentially Methylated Regions (…

149 天前 - … model of DNA methylome, we identified a total of 25,074 hypomethylated region
extension … and transcriptome in 3 somatic tissues (brain, liver, and skeletal muscle) and sperm …