… elicited in response to DSBs in ESCs and somatic cells that … stem cells (iPSCs), as first
demonstrated by Takahashi and Yamanaka [10]. The DDR responses in these pluripotent cells …

We have recently shown that the in vitro differentiation of human mesenchymal stem cells (hMSCs)
was accompanied by an increased sensitivity toward apoptosis; however, the …

… stem cells (MSC) to suppress alloresponsiveness is poorly understood. Herein, an allogeneic
mixed lymphocyte response … MSC, modulate immune responses and suggest that MSC …

… These doses can induce a large number of DNA double-strand breaks in every cell, including
in the small subset of adult stem cells. The first response of cells to these DNA breaks is …

… It was observed that DDR foci accumulate in haematopoietic stem cells from ageing wild-…
in which stem cells respond to DNA damage and, at least in mouse embryonic stem cells, p53 …

… response of MSCs to DSB stress, we passaged bone marrow derived MSCs in vitro, evaluating
their responses … of these clinically valuable stem cells. Given recent observations that …

… We have characterized the DNA damage response (DDR) and quality of DNA double-strand
break (DSB) repair in human embryonic stem cells (hESCs), and in vitro-derived neural cells…

… Inducible pluripotent stem cells also display a robust DNA damage response, but the stability
of … for repair of DNA double-strand breaks (DSBs). NHEJ (which operates throughout the …

… , and ISC culture systems now allow more direct evaluation of the ISC response to radiation.
… Better understanding of ISC responses to radiation-induced DNA damage is relevant to our …

… The DNA damage response pathway, possible target in glioma stem cells (GSC). After
DNA damage is sensed by the Mre11-Rad50-Nbs1 (MRN)/human single strand DNA binding …