… and severity of triple-negative breast cancer (TNBC); however, … obesity reprograms mammary
adipose tissue macrophages to … Unlike pro-inflammatory M1 macrophages that antagonize …

… more frequently observed in the adipose tissue nearby the breast cancer. Previous study …
benign breast disease was correlated with significantly increased odd ratios for breast cancer …

… accounts for the largest proportion of the breast and has also … of adipose tissue in BC
might be mediated by macrophages. The roles of macrophages in the breast tumor-stroma (breast …

… , containing higher numbers of macrophages, crown-like … of adipose tissue with tumor
cells contributes to macrophage … also a local role in breast cancer development through the …

… recruitment to metabolic syndrome, and monocyte-derived LAMs are recruited into obese
adipose tissue. Citation29 Subsequently, we performed single-cell sequencing and spatial …

… of adipose tissue macrophages (ATMs) are important contributing factors to the pathogenesis
of obesity-related diseases. Eventually, these biologically active polypeptides promote the …

… breast cancer, we first analyzed publicly accessible raw databases from Gene Expression
Omnibus (GEO) and The Cancer … expression was associated with breast cancer survival. We …

… It is expressed by many tissues and by adipocyte tissue macrophages. Visfatin induces BC
proliferation via ERK1/2 and AKT pathways [130] and induces a malignant potential in BC by …

… between adipocytes, macrophages, and breast cancer cells. Macrophages that are stimulated
with leptin promote invasion and metastasis of breast cancer cells. Adiponectin, which is …

… (MDM) isolated from the same morbidly obese patients, induced phenotypic changes and
activation of human breast cancer cells. To characterize the phenotypical differences between …