Progesterone receptor isoform ratio: a breast cancer prognostic and predictive factor for antiprogestin responsiveness
PA Rojas, M May, GR Sequeira, A Elia… - … the National Cancer …, 2017 - academic.oup.com
… Antiprogestins have induced different responses in clinical trials (reviewed in [20–22]). We
hypothesized that antiprogestins… investigate the responses of breast cancers with different PR …
hypothesized that antiprogestins… investigate the responses of breast cancers with different PR …
Antiprogestins in breast cancer treatment: are we ready?
CLM Lanari, V Wargon, PA Rojas, A Molinolo - 2012 - ri.conicet.gov.ar
… Graham JD, Yager ML, Hill HD, Byth K, O’Neill GM & Clarke CL 2005 Altered progesterone
receptor isoform expression remodels progestin responsiveness of breast cancer cells. …
receptor isoform expression remodels progestin responsiveness of breast cancer cells. …
Progestin and antiprogestin responsiveness in breast cancer is driven by the PRA/PRB ratio via AIB1 or SMRT recruitment to the CCND1 and MYC promoters
V Wargon, M Riggio, S Giulianelli… - … journal of cancer, 2015 - Wiley Online Library
… breast tumors. The main goal of this study was to evaluate (i) whether antiprogestin
responsiveness in breast cancer … and the coactivator AIB1 in mediating antiprogestin-induced …
responsiveness in breast cancer … and the coactivator AIB1 in mediating antiprogestin-induced …
Antiprogestins for breast cancer treatment: We are almost ready
A Elia, G Pataccini, L Saldain, L Ambrosio… - The Journal of Steroid …, 2024 - Elsevier
… antiprogestins in breast cancer prevention in women with BRCA1 mutations, and their use
for breast cancer … predict antiprogestin responsiveness. The effects of combined treatments of …
for breast cancer … predict antiprogestin responsiveness. The effects of combined treatments of …
Progesterone receptor isoform ratio dictates antiprogestin/progestin effects on breast cancer growth and metastases: a role for NDRG1
…, M Riggio, V Figueroa, CA Lamb… - … Journal of Cancer, 2022 - Wiley Online Library
… Murine mammary carcinomas from the MPA-induced breast cancer model classified according
to their mifepristone responsiveness, as responsive, or constitutively resistant were used. …
to their mifepristone responsiveness, as responsive, or constitutively resistant were used. …
The molecular biology of RU486. Is there a role for antiprogestins in the treatment of breast cancer?
KB Horwitz - Endocrine Reviews, 1992 - academic.oup.com
… responsiveness in the breast cancer cell line T-47D. J Biol Chem 266:18969 46. Aronica
SM, Katzenellenbogen BS 1991 Progesterone receptor regulation in uterine cells: stimulation …
SM, Katzenellenbogen BS 1991 Progesterone receptor regulation in uterine cells: stimulation …
Pre-clinical and clinical treatment of breast cancer with antiprogestins
JGM Klijn, B Setyono-Han, HJ Sander… - Human …, 1994 - academic.oup.com
… Antiprogestins form a new potential treatment modality for breast cancer and their mode
of action has been assessed in vitro on several breast cancer cell lines, in vivo in rats with …
of action has been assessed in vitro on several breast cancer cell lines, in vivo in rats with …
Effects of antiprogestins on the rate of proliferation of breast cancer cells
K Iwasaki, B Underwood, M Herman, S Dinda… - Molecular and cellular …, 1999 - Springer
… Guichon-Mentel A, Loosfelt H, Ragot T, Bailly A, Atger M, Misrahi M, Perricudet M, Milgrom
E: Receptors bound to antiprogestin form abortive complexes with hormone responsive …
E: Receptors bound to antiprogestin form abortive complexes with hormone responsive …
Leveraging antiprogestins in the treatment of metastatic breast cancer
S Kamaraju, AM Fowler, E Weil, KB Wisinski… - …, 2021 - academic.oup.com
… progesterone in endocrine-responsive breast cancer. The explanation … or antiprogestins
has been explored as breast cancer … -sensitive breast cancers may also respond well to either …
has been explored as breast cancer … -sensitive breast cancers may also respond well to either …
Progesterone antagonists and progesterone receptor modulators in the treatment of breast cancer
JGM Klijn, B Setyono-Han, JA Foekens - Steroids, 2000 - Elsevier
… Antitumor effects of single treatment with antiprogestins in postmenopausal patients with …
Estrogenic actions of RU486 in estrogen responsive human breast cancer MCF-7 cells. In: …
Estrogenic actions of RU486 in estrogen responsive human breast cancer MCF-7 cells. In: …
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