Epithelial–mesenchymal transition and breast cancer: Role, molecular mechanisms and clinical impact

C Foroni, M Broggini, D Generali, G Damia - Cancer treatment reviews, 2012 - Elsevier
… network, its putative role in the metastatic process and its implications in response/resistance
to the current and/or new approaching drugs in the clinical management of breast cancer. …

New insights into tumor-infiltrating B lymphocytes in breast cancer: clinical impacts and regulatory mechanisms

M Shen, J Wang, X Ren - Frontiers in immunology, 2018 - frontiersin.org
… have been recognized as a new hallmark of breast cancer (BC). The function seems to be
… give guide to clinical treatment. In this review, we give new insights into clinical impacts and …

PET/CT for patients with breast cancer: where is the clinical impact?

GA Ulaner - American Journal of Roentgenology, 2019 - Am Roentgen Ray Soc
… the greatest effect on clinical management of patients with breast cancer, novel radiotracers
and … for patients with breast cancer. National Comprehensive Cancer Network guidelines for …

Clinical impact of delaying initiation of adjuvant chemotherapy in patients with breast cancer

DM Gagliato, AM Gonzalez-Angulo, X Lei… - Journal of clinical …, 2014 - ascopubs.org
Purpose For patients with breast cancer (BC), the optimal time to initiation of adjuvant
chemotherapy (TTC) after definitive surgery is unknown. We evaluated the association between …

HER2 discordance between primary and metastatic breast cancer: assessing the clinical impact

NH Turner, A Di Leo - Cancer treatment reviews, 2013 - Elsevier
… , of paired samples of primary breast cancer and metastatic recurrence. … As the primary focus
of this review was the clinical impact of … Similarly, studies assessing bilateral breast cancer, …

Molecular mechanism and clinical impact of APOBEC3B-catalyzed mutagenesis in breast cancer

RS Harris - Breast Cancer Research, 2015 - Springer
… In conclusion, APOBEC3B mutagenesis is a major factor in breast cancer and many other
human malignancies and much additional basic, translational, and clinical work is needed to …

Assessing the clinical impact of prognostic factors: when is" statistically significant" clinically useful?

DF Hayes, B Trock, AL Harris - Breast cancer research and treatment, 1998 - Springer
… Very few tumor markers have been recommended for routine clinical care of patients with
breast cancer [1]. A framework to determine the clinical utility of tumor markers is required. In a …

Clinical impact of detection of loss of heterozygosity of BRCA1 and BRCA2 markers in sporadic breast cancer

MW Beckmann, F Picard, HX An… - … journal of cancer, 1996 - nature.com
… The development of familial and sporadic breast cancer is … -q12-13) in sporadic breast cancer,
polymerase chain reaction (… A total of 137 breast cancer and 15 benign breast specimens …

Clinical implications of the intrinsic molecular subtypes of breast cancer

A Prat, E Pineda, B Adamo, P Galván, A Fernández… - The Breast, 2015 - Elsevier
… Thus, this data suggests that subtyping within TN will not have a clinical impact based on
prognosis-only since no group has such an outstanding outcome that would allow avoiding …

Identifying microRNAs regulating B7-H3 in breast cancer: the clinical impact of microRNA-29c

MK Nygren, C Tekle, VA Ingebrigtsen, R Mäkelä… - … journal of cancer, 2014 - nature.com
… To our knowledge, the present study is the first demonstrating a clinical impact of miR-29c
in patients with breast cancer. It is tempting to speculate that this may at least partly be owing …