Clinical relevance of host immunity in breast cancer: from TILs to the clinic

P Savas, R Salgado, C Denkert, C Sotiriou… - Nature reviews Clinical …, 2016 - nature.com
… infiltrates observed in breast cancers, as well as data supporting the clinical relevance of
host … be used in the clinical setting. We also discuss the rationale for enhancing immunity in …

Heterogeneity of breast cancer: etiology and clinical relevance

V Almendro, G Fuster - Clinical and Translational Oncology, 2011 - Springer
… Insights about the evolution of breast cancer heterogeneity … of breast cancer heterogeneity
and its impact in the clinical … upon treatment are of major clinical relevance to identify the non-…

Clinical relevance of the triple-negative breast cancer concept: genetic basis and clinical utility of the concept

SC Linn, LJ Van't Veer - European Journal of Cancer, 2009 - Elsevier
… In this review, the molecular characterisation of triple-negative breast cancer, a proxy for
basal-like breast cancer, is described and findings have been put into clinical context. …

Shaping the future of biomarker research in breast cancer to ensure clinical relevance

MC Hinestrosa, K Dickersin, P Klein, M Mayer… - … Reviews Cancer, 2007 - nature.com
… of in situ and invasive breast cancer will be diagnosed among … The high burden of breast
cancer in women in the US and … Fewer than 10% of women who develop breast cancer have …

[HTML][HTML] Vasculogenic mimicry in breast cancer: clinical relevance and drivers

G Morales-Guadarrama, R García-Becerra… - Cells, 2021 - mdpi.com
… of breast cancer. Considering the clinical relevance of VM and its association with the tumor
… and clinicopathological parameters, further studies are granted to target VM in the clinic. …

[HTML][HTML] Micrometastatic spread in breast cancer: detection, molecular characterization and clinical relevance

T Fehm, V Müller, C Alix-Panabières, K Pantel - Breast Cancer Research, 2008 - Springer
… [1–3], this article will focus on the detection, molecular characterization and clinical relevance
of hematogeneous tumor cell spread as the most crucial step in breast cancer progression. …

Diversity of breast carcinoma: histological subtypes and clinical relevance

J Makki - Clinical medicine insights: Pathology, 2015 - journals.sagepub.com
… that have specific clinical course and outcome. Breast cancers can be classified into distinct
subgroups based on similarities in the gene expression profiles and molecular classification. …

[HTML][HTML] Clinical relevance of systemic monocytic-MDSCs in patients with metastatic breast cancer

C Bergenfelz, A Roxå, M Mehmeti… - Cancer Immunology …, 2020 - Springer
… light on the clinical impact of systemic Mo-MDSCs in breast cancer patients. An extended
knowledge of the systemic immune response is, therefore, extremely relevant in understanding …

Clinical relevance of the distribution of the lesions in 500 consecutive breast cancer cases documented in large‐format histologic sections

T Tot - … International Journal of the American Cancer Society, 2007 - Wiley Online Library
… and the extent of the disease in breast cancer cases. The objective of the current study was
to analyze a sufficiently large series of consecutive breast cancer cases with regard to the …

[HTML][HTML] Clinical relevance of TNM staging system according to breast cancer subtypes

YH Park, SJ Lee, EY Cho, YL Choi, JE Lee, SJ Nam… - Annals of oncology, 2011 - Elsevier
… of breast cancer biology based on molecular techniques allow us to divide breast cancer into
… , the TNM staging system still regards breast cancer as a single disease entity. Therefore, …