… DNA methylation and gene silencing in breast cancer, and suggest that inhibition of LSD2 in
combination with DNA methyltransferase … approach for epigenetic therapy of breast cancer. …

… cells, the presence of PRC2 can lead to recruitment of DNA methyltransferases (DNMTs)
resulting in de novo DNA methylation and more permanent repression of PRC2 target genes [9]…

… Thus, a change in DNA methylation profile is a hallmark of almost all human cancers,
including breast cancer. DNA methylation is mediated by DNA methyltransferases (DNMTs) that …

… , and thus response to ICIs in breast cancer, are actively being sought. Our … DNA
methyltransferase inhibitor (DMTi), potentiated cytotoxic CD8 + T cell responses in breast cancer, …

… Estrogen receptor (ER)-negative breast cancer cells display extensive methylation of the
ER gene CpG island and elevated DNA methyltransferase (DMT) expression compared to ER-…

… to have weak DNA methyltransferase activity. DNMT3a … DNA of patients with breast cancer
and tumors were successfully detected in eight of 24 patients with early-stage breast cancer. …

… of breast cancer, however, Wani and D’Ambrosio28 reported that the tumor grade and
metastatic potential of breast cancer … This study of patients with breast cancer showed that tumor …

… Currently, one of the most disputed hypotheses regarding breast cancer (BC) development
… the total activity of DNA methyltransferases (DNMT) and global DNA methylation (GDM) levels…

… and DNMT3b methyltransferase genes along with BRCA1 promoter methylation to better
define the epigenetic events involved in BRCA1 inactivation in sporadic breast cancer. These …

… oxidative DNA damage on the DNA methylation pattern of the tumor suppressor breast cancer
1 (… We found that oxidative DNA damage simultaneously induced DNA demethylation and …