CircRNA DNA methyltransferase 1 silence inhibits breast cancer development by regulating micoRNA‐485‐3p/zinc finger E‐box binding homeobox 1 axis

C Xie, J Li, C Xu, W Xiong… - Journal of Obstetrics and …, 2021 - Wiley Online Library
… Circular RNAs (circRNAs) are associated with tumorigenesis of breast cancer. Nevertheless,
how and whether circRNA DNA methyltransferase 1 (circ-DNMT1) controls breast cancer

Array-based DNA methylation profiling for breast cancer subtype discrimination

I Van der Auwera, W Yu, L Suo, L Van Neste… - PloS one, 2010 - journals.plos.org
breast tumor subtyping. We sought to determine whether the distinction of the inflammatory
breast cancer (… methyltransferase (DNMT) machinery, we compared the expression levels of …

Altered DNA methyltransferases promoter methylation and mRNA expression are associated with tamoxifen response in breast tumors

R Jahangiri, F Mosaffa, A Emami Razavi… - Journal of cellular …, 2018 - Wiley Online Library
… tissues to understand if overexpression of DNMTs associated with progression of breast
cancer and resistance incidence during tamoxifen treatment period. The promoter methylation of …

[HTML][HTML] Loss of the N-terminal methyltransferase NRMT1 increases sensitivity to DNA damage and promotes mammary oncogenesis

LA Bonsignore, JS Butler, CM Klinge, CES Tooley - Oncotarget, 2015 - ncbi.nlm.nih.gov
… a tumor suppressor involved in multiple modes of DNA repair. We observe that loss of N-terminal
methylation enhances breast cancer cell sensitivity to DSBs induced by etoposide and γ…

Identification of novel peptides targeting DNA methyltransferase 1 (DNMT-1) for breast cancer treatment

M Saragih, F Stephanie, AH Alkaff… - Revista Brasileira de …, 2020 - Springer
… of breast cancer cell proliferation and propagation. DNA methyltransferase (DNMT) is
responsible for DNA … Hence, inhibiting DNMT-1 is a promising way to block uncontrolled DNA

DNA methyltransferase inhibitors for cancer therapy

B Brueckner, D Kuck, F Lyko - The Cancer Journal, 2007 - journals.lww.com
… and demethylation and reactivation of the RARβ tumor suppressor gene in the MCF-7
breast cancer cell line. Induction of gene-specific demethylation by procainamide was also …

The DNA methyltransferase inhibitor, guadecitabine, targets tumor-induced myelopoiesis and recovers T cell activity to slow tumor growth in combination with adoptive …

AJ Luker, LJ Graham, TM Smith, C Camarena… - BMC immunology, 2020 - Springer
DNA methyltransferase inhibitor (DNMTi), decitabine. Using the aggressive murine breast
cancer … Guadecitabine was similarly effective in the E0771 model of murine breast carcinoma. …

Arginine methyltransferases as novel therapeutic targets for breast cancer

A Morettin, RM Baldwin, J Côté - Mutagenesis, 2015 - academic.oup.com
… of breast cancer (58). BRCA1 was shown to be methylated in both breast cancer cell lines
and patient breast … PRMT1 methylation of BRCA1 occurs within the DNA-binding region, …

DNA methylation in benign breast epithelium in relation to age and breast cancer risk

DM Euhus, D Bu, S Milchgrub, XJ Xie, A Bian… - Cancer Epidemiology …, 2008 - AACR
… During DNA replication, DNA methylation patterns are copied from the parent strand to
the daughter strand by the enzyme DNA methyltransferase (4). Methylated CpG patterns are …

The effect of dietary polyphenols on the epigenetic regulation of gene expression in MCF7 breast cancer cells

J Paluszczak, V Krajka-Kuźniak, W Baer-Dubowska - Toxicology letters, 2010 - Elsevier
… of DNMTs in human breast cancer MCF7 cell line and their effect on DNA and histone H3
methylation. All phytochemicals inhibited the DNA methyltransferase activity with betanin being …