CircRNA DNA methyltransferase 1 silence inhibits breast cancer development by regulating micoRNA‐485‐3p/zinc finger E‐box binding homeobox 1 axis
C Xie, J Li, C Xu, W Xiong… - Journal of Obstetrics and …, 2021 - Wiley Online Library
… Circular RNAs (circRNAs) are associated with tumorigenesis of breast cancer. Nevertheless,
how and whether circRNA DNA methyltransferase 1 (circ-DNMT1) controls breast cancer …
how and whether circRNA DNA methyltransferase 1 (circ-DNMT1) controls breast cancer …
Array-based DNA methylation profiling for breast cancer subtype discrimination
I Van der Auwera, W Yu, L Suo, L Van Neste… - PloS one, 2010 - journals.plos.org
… breast tumor subtyping. We sought to determine whether the distinction of the inflammatory
breast cancer (… methyltransferase (DNMT) machinery, we compared the expression levels of …
breast cancer (… methyltransferase (DNMT) machinery, we compared the expression levels of …
Altered DNA methyltransferases promoter methylation and mRNA expression are associated with tamoxifen response in breast tumors
R Jahangiri, F Mosaffa, A Emami Razavi… - Journal of cellular …, 2018 - Wiley Online Library
… tissues to understand if overexpression of DNMTs associated with progression of breast
cancer and resistance incidence during tamoxifen treatment period. The promoter methylation of …
cancer and resistance incidence during tamoxifen treatment period. The promoter methylation of …
[HTML][HTML] Loss of the N-terminal methyltransferase NRMT1 increases sensitivity to DNA damage and promotes mammary oncogenesis
LA Bonsignore, JS Butler, CM Klinge, CES Tooley - Oncotarget, 2015 - ncbi.nlm.nih.gov
… a tumor suppressor involved in multiple modes of DNA repair. We observe that loss of N-terminal
methylation enhances breast cancer cell sensitivity to DSBs induced by etoposide and γ…
methylation enhances breast cancer cell sensitivity to DSBs induced by etoposide and γ…
Identification of novel peptides targeting DNA methyltransferase 1 (DNMT-1) for breast cancer treatment
… of breast cancer cell proliferation and propagation. DNA methyltransferase (DNMT) is
responsible for DNA … Hence, inhibiting DNMT-1 is a promising way to block uncontrolled DNA …
responsible for DNA … Hence, inhibiting DNMT-1 is a promising way to block uncontrolled DNA …
DNA methyltransferase inhibitors for cancer therapy
B Brueckner, D Kuck, F Lyko - The Cancer Journal, 2007 - journals.lww.com
… and demethylation and reactivation of the RARβ tumor suppressor gene in the MCF-7
breast cancer cell line. Induction of gene-specific demethylation by procainamide was also …
breast cancer cell line. Induction of gene-specific demethylation by procainamide was also …
The DNA methyltransferase inhibitor, guadecitabine, targets tumor-induced myelopoiesis and recovers T cell activity to slow tumor growth in combination with adoptive …
… DNA methyltransferase inhibitor (DNMTi), decitabine. Using the aggressive murine breast
cancer … Guadecitabine was similarly effective in the E0771 model of murine breast carcinoma. …
cancer … Guadecitabine was similarly effective in the E0771 model of murine breast carcinoma. …
Arginine methyltransferases as novel therapeutic targets for breast cancer
A Morettin, RM Baldwin, J Côté - Mutagenesis, 2015 - academic.oup.com
… of breast cancer (58). BRCA1 was shown to be methylated in both breast cancer cell lines
and patient breast … PRMT1 methylation of BRCA1 occurs within the DNA-binding region, …
and patient breast … PRMT1 methylation of BRCA1 occurs within the DNA-binding region, …
DNA methylation in benign breast epithelium in relation to age and breast cancer risk
DM Euhus, D Bu, S Milchgrub, XJ Xie, A Bian… - Cancer Epidemiology …, 2008 - AACR
… During DNA replication, DNA methylation patterns are copied from the parent strand to
the daughter strand by the enzyme DNA methyltransferase (4). Methylated CpG patterns are …
the daughter strand by the enzyme DNA methyltransferase (4). Methylated CpG patterns are …
The effect of dietary polyphenols on the epigenetic regulation of gene expression in MCF7 breast cancer cells
J Paluszczak, V Krajka-Kuźniak, W Baer-Dubowska - Toxicology letters, 2010 - Elsevier
… of DNMTs in human breast cancer MCF7 cell line and their effect on DNA and histone H3
methylation. All phytochemicals inhibited the DNA methyltransferase activity with betanin being …
methylation. All phytochemicals inhibited the DNA methyltransferase activity with betanin being …