Folate receptor alpha expression is associated with increased risk of recurrence in triple-negative breast cancer

PS Ginter, PJ McIntire, X Cui, L Irshaid, Y Liu… - … breast cancer, 2017 - Elsevier
Folate receptor alpha (FOLR1) has been identified as a … in breast cancer. The limited studies
evaluating the role of FOLR1 in breast cancer have shown that FOLR1 protein expression is …

Folate receptor α associated with triple-negative breast cancer and poor prognosis

Z Zhang, J Wang, DE Tacha, P Li… - … of Pathology and …, 2014 - meridian.allenpress.com
Folate receptor α was expressed in 29% of the breast carcinomas in the current study …
breast carcinoma, consistent with previously reported studies, 4,11,12 although FRA expression

Folate receptor alpha (FRA) expression in breast cancer: identification of a new molecular subtype and association with triple negative disease

DJ O'Shannessy, EB Somers, J Maltzman, R Smale… - Springerplus, 2012 - Springer
… Here we describe and define the expression pattern of FRA in breast cancer using a … a
strong association of FRA expression with TNBC. FRA expressing breast cancers may represent a …

Folate receptor-α (FOLR1) expression and function in triple negative tumors

BM Necela, JA Crozier, CA Andorfer, L Lewis-Tuffin… - PloS one, 2015 - journals.plos.org
breast cancer, we compared expression of FOLR1 at the RNA and protein level in different
subtypes of human breast cancer [(hormone receptor … among subtypes of breast cancer, with …

[HTML][HTML] Concordance of folate receptor-α expression between biopsy, primary tumor and metastasis in breast cancer and lung cancer patients

LSF Boogerd, MC Boonstra, AJ Beck, A Charehbili… - Oncotarget, 2016 - ncbi.nlm.nih.gov
… on especially the majority of TN breast cancers and therefore, FRα could be an … expression
on both NSCLC and breast cancers and to determine concordance between FRα expression

Folate receptor α is associated with poor clinicopathological perspectives in breast carcinoma

NAER Aboulhagag, RF Torky, SA Fadel - Pathophysiology, 2018 - Elsevier
… Because of its potential as a tumor-specific target, we sought to examine the expression of
FRα in breast cancer in greater detail. To address this issue, and to assess the possibility of …

Folate receptor overexpression is associated with poor outcome in breast cancer

LC Hartmann, GL Keeney, WL Lingle… - … journal of cancer, 2007 - Wiley Online Library
… to examine the expression of the folate receptor in breast cancers in greater … folate
receptor-positive cells, we studied its expression in a set of good and poor-outcome breast cancers

Breast cancers: MR imaging of folate-receptor expression with the folate-specific nanoparticle P1133

R Meier, TD Henning, S Boddington, S Tavri, S Arora… - Radiology, 2010 - pubs.rsna.org
… of folate receptors (FRs) on breast cancer cells is a strong predictor of poor outcome in patients
with breast cancer. After adjustment for tumor size, nodal status, estrogen-receptor status, …

Folate receptor alpha as a tumor target in epithelial ovarian cancer

KR Kalli, AL Oberg, GL Keeney, TJH Christianson… - Gynecologic …, 2008 - Elsevier
… Unlike the more ubiquitously expressed reduced folate carrier and proton-coupled folate
strategies decreased the proliferation rate of breast cancer cell lines and increased their …

Anti-folate receptor alpha–directed antibody therapies restrict the growth of triple-negative breast cancer

A Cheung, J Opzoomer, KM Ilieva, P Gazinska… - Clinical Cancer …, 2018 - AACR
… FRα expression contributes to breast cancer growth To gain insights into FRα functions,
we evaluated FRα expression in 22 breast cancer cell lines by flow cytometry using the mAb …