Identification of fusion genes in breast cancer by paired-end RNA-sequencing
H Edgren, A Murumagi, S Kangaspeska, D Nicorici… - Genome biology, 2011 - Springer
… In this study, we describe the identification of 27 fusion genes from breast cancer samples
… the number of validated expressed fusion genes reported in breast cancer cells so far. This …
… the number of validated expressed fusion genes reported in breast cancer cells so far. This …
Characterization of fusion genes and the significantly expressed fusion isoforms in breast cancer by hybrid sequencing
… of expressed fusion isoforms. We applied IDP-fusion to the breast cancer cell line MCF-7 as
… discovery of fusion genes since these cells harbor more known gene fusions than any other …
… discovery of fusion genes since these cells harbor more known gene fusions than any other …
Are breast cancers driven by fusion genes?
PAW Edwards, KD Howarth - Breast Cancer Research, 2012 - Springer
… cancer cell lines and tumors, adding substantially to the tally of known fusion genes in breast
cancers. Fusion genes are formed when a structural rearrangement of the genome, such as …
cancers. Fusion genes are formed when a structural rearrangement of the genome, such as …
Identification of differentially expressed genes and typical fusion genes associated with three subtypes of breast cancer
R Wang, J Li, C Yin, D Zhao, L Yin - Breast Cancer, 2019 - Springer
… by the fusion gene to be involved in the breast cancer. Besides, we also discovered that the
most fusion genes were only existed in one breast cancer cell line, while only 6 fusion genes …
most fusion genes were only existed in one breast cancer cell line, while only 6 fusion genes …
G enomic hotspots but few recurrent fusion genes in breast cancer
… in 55 well-characterized breast cancer samples and 10 adjacent normal breast tissues, …
We explored the presence of fusion genes and defined their association with breast cancer …
We explored the presence of fusion genes and defined their association with breast cancer …
Frequent miRNA-convergent fusion gene events in breast cancer
H Persson, R Søkilde, J Häkkinen, AC Pirona… - Nature …, 2017 - nature.com
… largely unexplored function of fusion genes. Here, we show, using breast cancer as an
example, that miRNA host genes are specifically enriched in fusion genes and that many different…
example, that miRNA host genes are specifically enriched in fusion genes and that many different…
Identification of gene fusion transcripts by transcriptome sequencing in BRCA1-mutated breast cancers and cell lines
… find evidence of this gene fusion expressed in the panel of 57 breast cancer samples discussed
… While we observed some previously reported CNVs near the selected fusion genes, no …
… While we observed some previously reported CNVs near the selected fusion genes, no …
Fusion‐associated carcinomas of the breast: Diagnostic, prognostic, and therapeutic significance
… variants and their encoded proteins identified in breast cancer cell lines and tissues. Numbers
represent different exons in the corresponding wildtype genes or fusion genes. E9-E2 and …
represent different exons in the corresponding wildtype genes or fusion genes. E9-E2 and …
Perspective insight into future potential fusion gene transcript biomarker candidates in breast cancer
RN Kim, HG Moon, W Han, DY Noh - International Journal of Molecular …, 2018 - mdpi.com
… to the formation of fusion genes in breast cancer are, so far, … fusion genes recently identified
in breast cancer patients, including TCGA (The Cancer Genome Atlas) clinical breast cancer …
in breast cancer patients, including TCGA (The Cancer Genome Atlas) clinical breast cancer …
Characterization of the genomic features and expressed fusion genes in micropapillary carcinomas of the breast
… breast cancer and the recent identification of recurrent expressed fusion genes in breast
cancer… mutations affecting 273 genes, either recurrently mutated in breast cancer or DNA repair-…
cancer… mutations affecting 273 genes, either recurrently mutated in breast cancer or DNA repair-…
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- breast cancer fusion transcripts
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