… for these three factors nor their role in cancer has been fully … families of growth factors are
also relevant to breast cancer. … growth factors (PDGF) A and B, and fibroblast growth factors (…

… growth factor receptor are among the most notable cancer molecular targets identified to date
epidermal growth factor receptorepidermal growth factor … 20–25 % of breast cancers, is the …

… growth in vitro. Such data alone cannot definitively establish a role for autocrine growth factors
in human breast cancer cell … of data obtained with primary breast cancer cells and tissues. …

… human breast cancer cell line is under hormonal control. Our … has a growth inhibitory activity
on human breast cancer cell lines suggests autocrine and paracrine mechanisms of growth …

… growth factors for human breast cancer. We demonstrate that both IGF-I and IGF-II are potent
mitogens for breast cancer cells, and that the growth … by certain breast cancer cell lines and …

… negative and node-positive breast cancers. More recently, the expression of certain endothelial
growth factors has been tested. Among these, vascular endothelial growth factor (VEGF), …

… for transforming growth factors in human breast cancer: clinical correlates. Br J Cancer 61:612 …
transforming growth factor alpha and beta and epidermal growth factor receptor in primary …

… whether VPF has a role in breast cancer, we used in situ hybridization to study VPF mRNA
expression in normal breast tissue (13 specimens), comedo-type ductal carcinoma in situ (…

… that nerve growth factor (NGF), the prototypic neurotrophin, can be targeted in breast cancer
to … of human breast tumors, with anti-NGF immunoreactivity concentrated in the epithelial …

… growth factor (EGF) in 35 of 104 primary human breast … growth of a proportion of
poorprognosis oestrogen-receptor-negative tumours may be regulated by peptide growth factors …