The clinicopathological significance of lamin A/C, lamin B1 and lamin B receptor mRNA expression in human breast cancer

U Wazir, MH Ahmed, JM Bridger, A Harvey… - Cellular & molecular …, 2013 - Springer
breast cancer [47, 48]. In addition, we believe we are the first group report a role for lamin
B1 and LBR in human breast cancer. … envelope proteins in human breast cancer, which may …

Expression of Lamin A/C in early-stage breast cancer and its prognostic value

IM Alhudiri, CC Nolan, IO Ellis, A Elzagheid… - Breast cancer research …, 2019 - Springer
… This study aimed to evaluate expression and prognostic significance of lamin A/C in early-…
This study suggests lamin A/C plays a role in breast cancer and loss of its expression is …

[HTML][HTML] Loss of A-type lamin expression compromises nuclear envelope integrity in breast cancer

CD Capo-chichi, KQ Cai, J Smedberg… - … journal of cancer, 2011 - ncbi.nlm.nih.gov
… The lamin A/C–suppressed breast epithelial cells developed aneuploidy as determined by
both … proteins lamin A/C in breast cancer underlies the two hallmarks of cancer aberrations in …

Low lamin A levels enhance confined cell migration and metastatic capacity in breast cancer

ES Bell, P Shah, N Zuela-Sopilniak, D Kim, AA Varlet… - Oncogene, 2022 - nature.com
breast cancer cells frequently exhibit Akt-driven lower expression of the nuclear envelope
proteins lamin A/… , we report that variable expression of lamin A, and to lesser degree lamin C, …

Altered Lamin A/C splice variant expression as a possible diagnostic marker in breast cancer

A Aljada, J Doria, AM Saleh, SH Al-Matar… - Cellular Oncology, 2016 - Springer
… conclude that the Lamin C : Lamin A mRNA ratio is increased in breast cancer and that this
… of breast cancer and, possibly, also in liver, lung, thyroid, colon, ovary and prostate cancers. …

The expression of the senescence-associated biomarker lamin B1 in human breast cancer

T Saleh, A Alhesa, M El-Sadoni, N Abu Shahin… - Diagnostics, 2022 - mdpi.com
… In this work, we aimed to characterize lamin B1 expression in breast cancer tissue and the
change in protein expression levels that might occur in response to exposure to senescence-…

Global loss of a nuclear lamina component, lamin A/C, and LINC complex components SUN 1, SUN 2, and nesprin‐2 in breast cancer

A Matsumoto, M Hieda, Y Yokoyama… - Cancer …, 2015 - Wiley Online Library
lamin A/C expression in breast cancer tissue is consistent with previous data 12, 13. In addition,
we also showed that loss of nesprin-2 and lamin A/C protein expression … in breast cancer

Lamin B2 promotes the progression of triple negative breast cancer via mediating cell proliferation and apoptosis

CC Zhao, J Chen, LY Zhang, H Liu… - Bioscience …, 2021 - portlandpress.com
… Therefore, among these lamin proteins, LMNB2 is the most likely therapeutic target for the
treatment of breast cancer. As B-type lamins are constitutively expressed in most cell types, it …

Radiation therapy affects YAP expression and intracellular localization by modulating lamin A/C levels in breast cancer

G La Verde, V Artiola, M Pugliese… - … in Bioengineering and …, 2022 - frontiersin.org
… and the expression of the nuclear envelope protein lamin A/C… expression ratio, increasing
in healthy cells and decreasing in tumour ones, were accompanied by lower and higher lamin

Decreased and aberrant nuclear lamin expression in gastrointestinal tract neoplasms

SF Moss, V Krivosheyev, A De Souza, K Chin… - Gut, 1999 - gut.bmj.com
… use of lamin expression as a tumour marker, we therefore examined lamin expression in …
of breast cancer and in three of four cases of prostatic cancer studied. In non-small cell lung …