Leptomeningeal disease and breast cancer: the importance of tumor subtype

S Abouharb, J Ensor, ME Loghin, R Katz… - Breast cancer research …, 2014 - Springer
Breast cancer (BC) is one of the most common tumors to involve the leptomeninges. We
aimed to characterize clinical features and outcomes of patients with LMD based on BC …

Pharmacotherapy for leptomeningeal disease in breast cancer

R Bartsch, KJ Jerzak, L Larrouquere, V Müller… - Cancer Treatment …, 2023 - Elsevier
… known as leptomeningeal metastases or leptomeningeal … often excluded from clinical trials
in breast cancer, with very few … strategies for patients with breast cancer and LMD. We explore …

Breast leptomeningeal disease: a review of current practices and updates on management

NB Figura, VT Rizk, AJ Armaghani, JA Arrington… - Breast Cancer Research …, 2019 - Springer
… The metastatic spread of breast cancer to the leptomeninges … shedding into the CSF from
adjacent CNS disease [7, 8]. The … increase the risk for leptomeningeal seeding, especially if the …

Treatment and prognosis of leptomeningeal disease secondary to metastatic breast cancer: a single-centre experience

B Kingston, H Kayhanian, C Brooks, N Cox… - The Breast, 2017 - Elsevier
… We report the treatment and outcomes of 182 breast cancer patients diagnosed with
leptomeningeal disease over a 10-year period in one single centre in the United Kingdom. Our …

Evolving management of HER2+ breast cancer brain metastases and leptomeningeal disease

MN Mills, W King, A Soyano, Y Pina… - Journal of Neuro …, 2022 - Springer
… factor receptor 2 (HER2)-positive breast cancer are at a particularly high risk of breast cancer
brain metastasis (BCBM) and leptomeningeal disease (LMD). Improvements in systemic …

[HTML][HTML] High-dose intravenous methotrexate in the management of breast cancer with leptomeningeal disease: Case series and review of the literature

JT Kapke, RJ Schneidewend, ZA Jawa… - … /Oncology and Stem Cell …, 2019 - Elsevier
Leptomeningeal metastasis (LM) in breast cancer is associated with significant morbidity …
for LM in breast cancer. We present three cases of metastatic breast cancer and LM with …

Breast cancer and leptomeningeal disease (LMD): hormone receptor status influences time to development of LMD and survival from LMD diagnosis

S Yust-Katz, P Garciarena, D Liu, Y Yuan… - Journal of neuro …, 2013 - Springer
cancer patients. The aim of this study was to identify risk factors related to survival and time
to development of LMD in breast cancer patients. A retrospective analysis of breast cancer

Breast cancer patients with brain metastases or leptomeningeal disease: 10‐year results of a national cohort with validation of prognostic indexes

T Znidaric, J Gugic, T Marinko… - The Breast …, 2019 - Wiley Online Library
Abstract Development of brain metastasis (BM) and leptomeningeal (LM) disease in breast
cancer (BC) patients indicates poor prognosis and impairs patients’ quality of life. Prognostic …

Leptomeningeal disease following stereotactic radiosurgery for brain metastases from breast cancer

DM Trifiletti, KD Romano, Z Xu, KA Reardon… - Journal of neuro …, 2015 - Springer
… control of breast cancer systemic disease and brain metastasis in recent decades, patients
with metastatic breast cancer are at increased risk for LMD compared to other cancers [7–10], …

Characteristics and outcomes of patients with breast cancer with leptomeningeal metastasis

A Morikawa, L Jordan, R Rozner, S Patil, A Boire… - … breast cancer, 2017 - Elsevier
… The objectives of this retrospective study were to examine a modern cohort of patients
with breast cancer diagnosed with leptomeningeal disease at Memorial Sloan Kettering …