Obesity, leptin and breast cancer: epidemiological evidence and proposed mechanisms

S Andò, L Gelsomino, S Panza, C Giordano… - Cancers, 2019 - mdpi.com
… association between obesity and breast cancer. … obesity-associated changes may affect
breast malignancy, and we will outline the role of the obesity cytokine leptin in this type of cancer

Linkage between obesity leptin and breast cancer

MF Atoum, F Alzoughool… - Breast Cancer: Basic …, 2020 - journals.sagepub.com
breast tumor cells and the surrounding microenvironment. This review discussed the inverse
… between obesity and breast cancer among premenopausal breast cancer females and the …

Obesity and breast cancer: role of leptin

F Sánchez-Jiménez, A Pérez-Pérez… - Frontiers in …, 2019 - frontiersin.org
breast cancer cells. Traditionally, the two most important adipokines associated with the
development of breast cancer related to obesity are leptin, … function in obesity-related breast

Obesity hormone leptin: a new target in breast cancer?

E Surmacz - Breast Cancer Research, 2007 - Springer
leptin that acts upon breast cancer cells? Until now, the association between circulating leptin
levels and breast cancer or breast cancer … serum leptin was associated with breast cancer

Leptin, obesity and breast cancer: progress to understanding the molecular connections

I Barone, C Giordano, D Bonofiglio, S Andò… - Current Opinion in …, 2016 - Elsevier
obesity on breast cancer [7… leptin on breast carcinogenesis. We will also envision the potential
therapeutical strategies targeting leptin actions in breast cancer patients, especially obese

Increased expression of leptin and the leptin receptor as a marker of breast cancer progression: possible role of obesity-related stimuli

C Garofalo, M Koda, S Cascio, M Sulkowska… - Clinical Cancer …, 2006 - AACR
… whether the leptin system could become a target in breast cancer therapy, we examined
the expression of leptin and its receptor (ObR) in primary and metastatic breast cancer and …

Leptin and breast cancer: an overview

M Artac, K Altundag - Medical oncology, 2012 - Springer
… In obese humans, high plasma levels of leptin are correlated with increased fat mass and
the development of resistance to insulin [13, 14]. These data indicate that hormones seem to …

Obesity and breast cancer: status of leptin and adiponectin in pathological processes

ME Grossmann, A Ray, KJ Nkhata… - Cancer and Metastasis …, 2010 - Springer
… On the other hand, the role of serum leptin levels in breast cancer appears to be more … that
serum leptin levels are increased in women with breast cancer but others have found leptin to …

Leptin signaling in breast cancer: an overview

D Cirillo, AM Rachiglio, R La Montagna… - Journal of cellular …, 2008 - Wiley Online Library
leptin system might play an important role in breast cancer … of expression of leptin in obese
women; the ability of leptin to … of expression of leptin and its receptors in breast cancer cells; …

Adverse effects of obesity on breast cancer prognosis, and the biological actions of leptin

DP Rose, EM Gilhooly… - … journal of oncology, 2002 - spandidos-publications.com
… , and the related reduced breast cancer survival, occur in … The mechanisms by which obesity
affects breast cancer risk … role in obesity-mediated breast cancer progression, is leptin. This …