… pattern has implications on our understanding of how DNA methylation patterns are
disrupted in cancer and DNA methylation targeted therapy. Thus, it is proposed that a bilateral …

… cancer types. This review will briefly discuss basic aspects of DNA methylation, recent
advances in DNA … of gene transcriptional regulation built on methylated CpGs. In particular, we …

… of DNA methylation-based markers in pretherapeutic sera of breast cancer patients. We …
form of adjuvant systemic treatment, because this group of patients has the greatest potential for …

… by gene‑specific DNA methylation, suggesting novel … in patients with BC resistant to
anticancer treatment. The aim of the present review was to provide an update on DNA methylation …

… DNA methylation analysis is a rapidly developing field, a reproducible epigenetic blood-based
assay for diagnosis and follow-up of breast cancer … serum DNA methylation assays and to …

… Our results provide evidence that well-defined DNA methylation profiles enable breast cancer
… biomarker for prognostication and therapeutic stratification of patients with breast cancer. …

… Of these 35 markers, we identified five genes whose DNA methylation correlated with
HER-2… score 0 breast cancer cases, we confirmed the higher prevalence of DNA methylation of …

… To clarify the functional relevance of DNA methylation, we evaluated the direct … methylation
level of gene regions in an independent set of 104 BC patients, where both DNA methylation …

… DNA sources that could facilitate integration of methylation tests in clinical practice. In breast
cancer, DNA methylation has … factor 2 (PITX2) DNA methylation has been validated using a …

… breast cancer and other diseases. Here, I review the scientific basis for … DNA methylation
signatures in breast cancer classification and prognosis. I discuss the role of DNA methylation …