PD-L1 expression in triple-negative breast cancer

EA Mittendorf, AV Philips, F Meric-Bernstam… - Cancer immunology …, 2014 - AACR
… differential PD-L1 expression … PD-L1, we next performed LCM to isolate breast cancer cells
from primary tumors. Following RNA extraction, qRT-PCR confirmed the presence of PD-L1

PD-1/PD-L1 targeting in breast cancer: the first clinical evidences are emerging—a literature review

G Planes-Laine, P Rochigneux, F Bertucci, AS Chrétien… - Cancers, 2019 - mdpi.com
… , most clinical investigations of PD-1/PD-L1 targeting have been … breast cancer, including
HER2-positive and luminal cancers. … of PD-1/PD-L1-based therapeutics in breast cancer, from …

PD-1/PD-L1 pathway in breast cancer

F Schütz, S Stefanovic, L Mayer, A von Au… - Oncology research and …, 2017 - karger.com
PD-1 or PD-L1 with specific antibodies like pembrolizumab or atezulizumab. In breast
cancer, potential response was demonstrated in metastatic triple-negative breast cancers. …

Understanding PD-L1 testing in breast cancer: a practical approach

R Erber, A Hartmann - Breast care, 2020 - karger.com
… triple negative breast cancer (mTNBC), if the tumor-associated immune cells express …
other PD-L1 tests are reliable and of clinical value to predict the response of breast cancer

[HTML][HTML] Expression of PD-L1 and prognosis in breast cancer: a meta-analysis

M Zhang, H Sun, S Zhao, Y Wang, H Pu, Q Zhang - Oncotarget, 2017 - ncbi.nlm.nih.gov
… association between PD-L1 expression and OS in breast cancer patients… PD-L1 overexpression
was associated with shorter OS in patients with breast cancer than the absence of PD-L1

Prognostic significance of PD-L1 and PD-L2 in breast cancer

MZ Baptista, LO Sarian, SFM Derchain, GA Pinto… - Human pathology, 2016 - Elsevier
… To assess PD-L1 and PD-L2 expressions, we conducted immunohistochemistry studies
using a breast cancer tissue microarray encompassing a total of 192 breast cancer cases, …

Immunotherapy in breast cancer: the emerging role of PD-1 and PD-L1

F Bertucci, A Gonçalves - Current oncology reports, 2017 - Springer
… review is to summarize the data regarding PD-L1 expression in breast cancer and the results
of first clinical trials with PD-1 or PD-L1 inhibitors in patients with metastatic breast cancer. …

PD-L1 status in breast cancer: Current view and perspectives

S Vranic, FS Cyprian, Z Gatalica, J Palazzo - Seminars in cancer biology, 2021 - Elsevier
… most important aims in the current research in breast immunotherapy. In the present review,
we … (PD-1/PD-L1) in breast cancer and explore the predictive aspects in the PD-L1 testing. …

[HTML][HTML] Prognostic and predictive value of PDL1 expression in breast cancer

R Sabatier, P Finetti, E Mamessier, J Adelaide… - Oncotarget, 2015 - ncbi.nlm.nih.gov
… correlation between PDL1 tumor expression and responses. We retrospectively analyzed
PDL1 mRNA expression in 45 breast cancer cell lines and 5,454 breast cancers profiled using …

PD-L1 expression is increased in a subset of basal type breast cancer cells

H Soliman, F Khalil, S Antonia - PloS one, 2014 - journals.plos.org
PD-L1 expression. This study identified a subset of basal breast cancer cells lines with much
higher PD-L1 … Molecular and pathologic data suggests that these high PD-L1 expressing …