Stratification of women according to their risk of breast cancer based on polygenic risk scores
(PRSs) could improve screening and prevention strategies. Our aim was to develop PRSs, …

… risk models, the more personalised risk assessment derived from PRS, help identify women
at higher risk of breast cancer … This review describes the role of PRS in breast cancer risk …

… In summary, the polygenic risk score is an independent predictor of breast cancer risk
that may improve identification of high-risk women in both Caucasian and East Asians. The …

… common breast cancer susceptibility single nucleotide polymorphisms (SNPs), summarised
as polygenic risk scores … between standardised polygenic risk scores and breast cancer risk. …

Previous research has shown that polygenic risk scores (PRSs) can be used to stratify women
according to their risk of developing primary invasive breast cancer. This study aimed to …

… modest breast cancer risk that, in aggregate, account for considerable breast cancer …
development and empirical validation of an SNP-based polygenic breast cancer risk score. …

… -SNV score with modification of breast cancer risk in PV carriers, we constructed multivariable
logistic regression models testing the association of the 86-SNV score with breast cancer …

… the risk of developing breast cancer. We previously described a 77-SNP polygenic risk
score (PRS) for breast cancer; women in the top 1% of the PRS were at 3-fold increased risk of …

… This study assessed the joint association of pathogenic variants (PVs) in breast cancer (BC)
predisposition genes and polygenic risk scores (PRS) with BC in the general population. …

We evaluated the joint associations between a new 313-variant PRS (PRS 313 ) and
questionnaire-based breast cancer risk factors for women of European ancestry, using 72 284 …