[HTML][HTML] Preclinical characteristics of the irreversible pan-HER kinase inhibitor neratinib compared with lapatinib: implications for the treatment of HER2-positive and …

DM Collins, NT Conlon, S Kannan, CS Verma, LD Eli… - Cancers, 2019 - mdpi.com
… This review focuses on preclinical findings regarding … -depth and comprehensive review of
preclinical data. Clinical trials … Despite their similarities, multiple distinguishing characteristics

Experimental breast cancer models: preclinical imaging perspective

U Korkmaz, F Ustun - Current Radiopharmaceuticals, 2021 - ingentaconnect.com
… The advantages and disadvantages of the use of small animals in the preclinical breast
cancer … Therefore, when selecting a model for the preclinical study, these characteristics of the …

A new model of patient tumor-derived breast cancer xenografts for preclinical assays

E Marangoni, A Vincent-Salomon, N Auger… - Clinical cancer …, 2007 - AACR
… Therefore, a preclinical model of breast cancer must be … Such a model of breast cancers
could identify new therapeutic … that breast cancer xenografts conserve the characteristics of …

Characterization of triple‐negative breast cancer preclinical models provides functional evidence of metastatic progression

JJ Arroyo‐Crespo, A Armiñán… - … journal of cancer, 2019 - Wiley Online Library
preclinical models that faithfully reproduce the clinical scenario. We describe two preclinical
cancer cells for lipids and cholesterol,34 a characteristic now considered a hallmark of …

Effects of the antiestrogen tamoxifen and the aromatase inhibitor letrozole on serum hormones and bone characteristics in a preclinical tumor model for breast cancer

NP Núñez, D Jelovac, L Macedo, D Berrigan… - Clinical cancer …, 2004 - AACR
breast cancer cell growth and increased BMD but caused uterine hypertrophy in this preclinical
model of postmenopausal breast cancer… risk of endometrial cancer risk and osteoporosis) …

Preclinical studies of molecular-targeting diagnostic and therapeutic strategies against breast cancer

T Fujii, G Yokoyama, H Takahashi, R Namoto… - Breast cancer, 2008 - Springer
… To clarify the role of PKC in the breast cancer cell, we have … the cell cycle by treating the
breast cancer cell line SKBR-3 with … characteristics through HER2-dependent pathways in breast

Screening for preclinical disease: test and disease characteristics

CR Herman, HK Gill, J Eng… - American journal of …, 2002 - Am Roentgen Ray Soc
… Diagnosing and treating breast cancer during the preclinical phase result in a higher … 5-year
patient survival rate than when breast cancer is diagnosed during the clinical phase [14]. …

[HTML][HTML] Antitumor properties of curcumin in breast cancer based on preclinical studies: a systematic review

KA Barcelos, CR Mendonça, M Noll, AF Botelho… - Cancers, 2022 - mdpi.com
breast cancer reported in preclinical in vitro and in vivo animal models. We used five databases
to search for preclinicalCharacteristics of the in vitro studies included in the systematic …

Preclinical and clinical evaluation of intraductally administered agents in early breast cancer

V Stearns, T Mori, LK Jacobs, NF Khouri… - Science translational …, 2011 - science.org
… ) in two preclinicalpreclinical studies, we also initiated a phase 1 clinical trial to establish
the logistics of intraductal administration in an outpatient setting to women with breast cancer

[HTML][HTML] Identification of human triple-negative breast cancer subtypes and preclinical models for selection of targeted therapies

BD Lehmann, JA Bauer, X Chen… - The Journal of …, 2011 - Am Soc Clin Investig
… that have stem cell-like characteristics, and CD44–CD24+ … breast cancer cell types and
identify targets such as JAK2 and Stat3 that may lead to more specific and effective breast cancer