A Novel Preclinical Murine Model to Monitor Inflammatory Breast Cancer Tumor Growth and Lymphovascular Invasion

AG Rickard, DS Sannareddy, A Bennion, P Patel… - Cancers, 2023 - mdpi.com
cancer, is often misdiagnosed due to its unique presentation … Various breast cancer cells
stably transfected to express … vessel characteristics can be expanded to investigate other cancer

Activity of preclinical and phase I clinical trial of a novel androgen receptor antagonist GT0918 in metastatic breast cancer

H Li, G Song, Q Zhou, R Ran, H Jiang, R Zhang… - Breast Cancer Research …, 2021 - Springer
… evaluated in AR expression breast cancer cells and in breast cancer xenograft model. A 3
+ 3 phase I dose-escalation study was launched in Peking University Cancer Hospital. The …

Local transdermal therapy to the breast for breast cancer prevention and DCIS therapy: preclinical and clinical evaluation

O Lee, D Ivancic, S Allu, A Shidfar, K Kenney… - Cancer chemotherapy …, 2015 - Springer
… by women at high risk of breast cancer has been low. Reasons … , breast cancer prevention
requires only that the breast be … The participant characteristics were similar between groups (…

Recombinant human erythropoietin in combination with chemotherapy increases breast cancer metastasis in preclinical mouse models

BD Hedley, JE Chu, DG Ormond, MS Beausoleil… - Clinical Cancer …, 2011 - AACR
… However, minimal preclinical data are available about the … human breast cancer cells using
in vitro assays and preclinical … Effect of rHuEPO on in vitro growth characteristics of MDA-MB-…

Patient-derived xenograft models of breast cancer and their predictive power

JR Whittle, MT Lewis, GJ Lindeman, JE Visvader - Breast cancer research, 2015 - Springer
… PDX models have been shown to retain the principal molecular characteristics of the … PDX
models for the preclinical testing of immunotherapies in breast cancer. Rather, syngeneic mice …

Preclinical and clinical studies of interferons and interferon inducers in breast cancer

EC Borden, FR Balkwill - Cancer, 1984 - Wiley Online Library
Preclinical and clinical studies suggest interferons and interferon inducers have antitumor
activity for breast … of freshly derived and continuously passaged breast carcinoma cells in vitro, …

Frequency, impact and a preclinical study of novel ERBB gene family mutations in HER2-positive breast cancer

N Elster, S Toomey, Y Fan… - … in medical oncology, 2018 - journals.sagepub.com
… We performed Agena MassArray analysis of 227 HER2+ breast cancer samples to identify
the … mutant, ER positive) HER2+ breast cancer cell lines for functional in vitro experiments. …

Discovery and validation of breast cancer early detection biomarkers in preclinical samples

CI Li - Hormones and Cancer, 2011 - Springer
… Cases and controls were ascertained from the WHI OS, and the characteristics of cases
and controls in our discovery and independent validation sets are shown in Table 1. Controls …

Orthotopic transplantation of breast tumors as preclinical models for breast cancer

X Lv, LE Dobrolecki, Y Ding, JM Rosen… - JoVE (Journal of …, 2020 - jove.com
Preclinical models that faithfully recapitulate tumor heterogeneity and therapeutic response
are critical for translational breast cancer research. Immortalized cell lines are easy to grow …

In vivo models in breast cancer research: progress, challenges and future directions

I Holen, V Speirs, B Morrissey… - Disease models & …, 2017 - journals.biologists.com
… varied uses of these models in breast cancer research, their strengths, … breast cancer; what
are the appropriate models of metastatic disease; can we use models to carry out preclinical