Role of the tumor microenvironment in breast cancer

SD Soysal, A Tzankov, SE Muenst - Pathobiology, 2015 - karger.com
… in the breast cancer microenvironment as a … breast cancer microenvironment, the alterations
in molecular signatures of cells comprising this microenvironment, their interplay with cancer

Molecular characterization of the tumor microenvironment in breast cancer

M Allinen, R Beroukhim, L Cai, C Brennan… - Cancer cell, 2004 - cell.com
… in the tumor microenvironment and interactions among various cell types in breast cancer
and … cell type composing normal breast tissue and in situ and invasive breast carcinomas. We …

Stromal cells in tumor microenvironment and breast cancer

Y Mao, ET Keller, DH Garfield, K Shen… - Cancer and Metastasis …, 2013 - Springer
microenvironment is a fertile ground for the development of novel … of tumor stroma interacting
with breast cancer cells, with … in breast cancer therapy associated with other tumor stromal …

Breast cancer models: Engineering the tumor microenvironment

G Bahcecioglu, G Basara, BW Ellis, X Ren, P Zorlutuna - Acta biomaterialia, 2020 - Elsevier
… (ECM) and thus do not represent the tumor microenvironment (TME). As an alternative …
of the breast cancer TME, and then discuss the current state of the pre-clinical breast cancer

The breast tumor microenvironment: role in cancer development, progression and response to therapy

S Mittal, NJ Brown, I Holen - Expert review of molecular diagnostics, 2018 - Taylor & Francis
… of the microenvironment for their … breast cancer outcome. Expert commentary: Despite the
importance in the development of breast cancer, the contribution of the microenvironment is …

Breast cancer stem cells, cytokine networks, and the tumor microenvironment

H Korkaya, S Liu, MS Wicha - The Journal of clinical …, 2011 - Am Soc Clin Investig
… These cancer stem cells (CSCs) are regulated by complex interactions with the components
of the tumor microenvironment — including mesenchymal stem cells, adipocytes, tumor

Cancer-associated fibroblasts as key regulators of the breast cancer tumor microenvironment

JM Houthuijzen, J Jonkers - Cancer and Metastasis Reviews, 2018 - Springer
… as influencing tumor cell survival and metastasis. This review discusses the impact of CAFs
on breast cancer biology and highlights their heterogeneity, origin and their role in tumor

Gene expression profiling of the tumor microenvironment during breast cancer progression

XJ Ma, S Dahiya, E Richardson, M Erlander… - Breast cancer …, 2009 - Springer
… Our results suggest that the tumor microenvironment participates in tumorigenesis even
before tumor cells invade into stroma, and that it may play important roles in the transition from …

Tumor microenvironment in breast cancer—updates on therapeutic implications and pathologic assessment

JJ Li, JY Tsang, GM Tse - Cancers, 2021 - mdpi.com
… The tumor microenvironment (TME) in breast cancer plays important roles in tumor behavior
and … This review covers the current understanding of the TME of breast cancer, its pathologic …

Tumor microenvironment of metastasis and risk of distant metastasis of breast cancer

TE Rohan, X Xue, HM Lin, TM D'Alfonso… - … the National Cancer …, 2014 - academic.oup.com
… We have identified this intravasation microenvironment in human breast cancer samples
using a triple immunostain for paraffin-embedded tissue that simultaneously labels …