The distribution of some commonly used drugs in human breast milk

JWA Findlay - Drug Metabolism Reviews, 1983 - Taylor & Francis
drug entry into milk, specific transport mechanisms for facilitating drug entry into human breast
milk … Numerous other factors will affect the extent of drug entry into milk and the amount to …

Excretion of drugs in human breast milk

RM Welch, JWA Findlay - Drug metabolism reviews, 1981 - Taylor & Francis
… know the amount of drug reaching the infant through breast milk. A … and elimination of drugs
from human breast milk and the … Presumably, the ready entry of codeine into milk reflects the …

Determinants and consequences of drug excretion in breast milk

JT Wilson - Drug metabolism reviews, 1983 - Taylor & Francis
… These changes conceivably influence drug entry into milk and formation of drugbreast
and milk yield [ 231. Excretion of a high-clearance and/or highly lipidsoluble drug in breast milk

Analgesie drugs in breast milk and plasma

JWA Findlay, RL DeAngelis… - Clinical …, 1981 - Wiley Online Library
milk, but we could find no published data on this aspect of the disposition of phenacetin. We
could find no true kinetic data for these drugs in human breast milkentry of codeine into milk

Drugs and chemical contaminants in human breast milk

A Anadón, MR Martínez-Larrañaga, I Ares… - Reproductive and …, 2017 - Elsevier
… The main principles of drug excretion into breast milk and the different determinants such
as the age-dependent factors affecting gastrointestinal absorption and the resulting …

Prediction of drug transfer into milk considering breast cancer resistance protein (BCRP)-mediated transport

N Ito, K Ito, Y Ikebuchi, Y Toyoda, T Takada… - Pharmaceutical …, 2015 - Springer
… the avoidance of drug transfer into milk and toxicity in breast-fed … actually investigated drug
transfer into milk, necessitating the … between milk and plasma governs drug transfer into milk, …

Pharmacokinetics, placental and breast milk transfer of antiretroviral drugs in pregnant and lactating women living with HIV

EM Hodel, C Marzolini, C Waitt… - Current …, 2019 - ingentaconnect.com
… out of the apical placental membrane thus preventing the entry of potentially harmful drugs
in the fetal circulation [101]. Members of the multidrug resistance-related protein (MRP) are …

Models and methods for predicting drug transfer into human milk

JC Fleishaker - Advanced drug delivery reviews, 2003 - Elsevier
drug partitioning between milk and plasma. In vivo studies may be necessary to assess active
processes that may either transport drugs into or out of breast milk… of drugs into breast milk

[HTML][HTML] Computational Approach to Drug Penetration across the Blood-Brain and Blood-Milk Barrier Using Chromatographic Descriptors

W Karolina, R Agata, B Elżbieta - Cells, 2023 - mdpi.com
… different routes of entry of drugs into the brain and milk, an … ) between the bioavailability of
the drug in breast milk M/P with … the risk of drug penetration into breast milk. The danger of …

[HTML][HTML] Transporters in the mammary gland—contribution to presence of nutrients and drugs into milk

AM García-Lino, I Álvarez-Fernández… - Nutrients, 2019 - mdpi.com
… found in milk play an important role in the nourishment of breast-… Conversely, milk may
contain substances—drugs, pesticides… The transfer of these compounds into milk is unavoidably …