… silica nanoparticles (SiO 2 NPs) exposure to human normal liver HL-7702 cells and rat normal
liver BRL-3A … cytotoxicity in HL-7702 cells than BRL-3A cells. Reactive oxygen species (…

… As shown in Figure 3A , the supernatants of the KCs stimulated … BRL cells were treated with
the supernatant of Kupffer cells stimulated by different concentrations of silica nanoparticles (…

… Silica nanoparticles (SiNPs) have been found to pass through biological barriers and get
distributed in the human body. They induce cell apoptosis via various mechanisms in body …

… due to exposure to silica nanoparticles. Further studies on the mechanism by which silica
nanoparticles induce the Nrf-2–ERK MAP kinase pathway, to more clearly elucidate the silica-…

… Biomedical applications of mesoporous silica nanoparticles (MSNs) require efficient cellular
uptake and low toxicity. The purpose of this study is to investigate the cellular uptake and …

… Silica nanoparticles (SiNPs) are promising drug carriers for ophthalmic drug delivery. However,
little … Table 1 The size and zeta potential of silica nanoparticles investigated in this study. …

… Treatment of silica nanoparticles … silica nanoparticles increased the level of nitric oxide
released from the cultured macrophage cell line. These results suggested that silica nanoparticles …

… In this study, ldk-chitosan nanoparticles were administered to a rat pancreatic cell line to
study the effects of ldk-chitosan nanoparticles on apoptosis in pancreatic cells induced by …

… Therefore, the toxicity of silica nanoparticles should be evaluated independently in every
target organ system by means of both in vivo and in vitro toxicity tests. For the ocular system, no …

… Here we describe our development of polyp-targeting, fluorescently-labeled mesoporous
silica nanoparticles (MSNs) that serve as targeted endoscopic contrast agents for the early …