… interact with G protein-coupled receptors (GPCRs). Here we … can inactivate these
spontaneously active receptors; (iii) the … use of β 2 -adrenoceptor agonists in the treatment of …

… Intracellular signaling following β 2 -adrenoceptor activation is largely affected through a …
the importance of β 2 -adrenoceptor polymorphisms to the asthma phenotype. However, the …

… addition to impaired β 2 -adrenergic responses in asthma, β 2 -adrenergic agonists may make
asthma worse, … For example, regular β 2 -adrenoceptor agonist use may enhance airway …

… , lacked bronchial selectivity and had … β 2 -adrenoceptors ( β 2 -receptors) located in
bronchial smooth muscle and have less cardiotoxicity. Traditional β 2 -adrenoceptor agonists ( β 2 -…

… Asthma is a polygenic disease for which no clear genotype-… of asthma per se, variant forms
of the β 2 -adrenoceptor (β 2 -… as bronchial hyper-responsiveness (BHR) and responses to β2-…

… might be in linkage disequilibrium, it is likely that large populations will have to be studied
to determine the importance of β 2 -adrenoceptor polymorphisms to the asthma phenotype. …

… activation of beta adrenergic receptors (/3AR) in asthma, when he wrote that "asthma is
immediately … , are now known to influence airway caliber in asthmatic patients by stimulating/32 …

… Inhaled β 2 -adrenoceptor agonists are by far the most effective and safe bronchodilators
currently available. They have not been surpassed by any other bronchodilating principle. The …

… effects of β 2 -adrenoceptor agonists. The beneficial effects of β 2 -adrenoceptor agonists are
… the relief of the symptoms of bronchial asthma and chronic obstructive pulmonary disease (…

… searched for a definite diagnosis of bronchial asthma, and 143 patients were enrolled in this
… 70%, which met the diagnostic criteria for asthma of the American Thoracic Society. Clinical …