[HTML][HTML] Advances in cancer immunotherapy 2019–latest trends

S Kruger, M Ilmer, S Kobold, BL Cadilha… - … & Clinical Cancer …, 2019 - Springer
… of CAR T cells in B cell malignancies to other hematological and solid cancer types are …
Tisagenlecleucel and axicabtagen-ciloleucel were the first two cellular cancer immunotherapies

In vitro and in vivo imaging of initial BT-cell interactions in the setting of B-cell based cancer immunotherapy

…, K Wennhold, S Balkow, E Kondo, B Bölck… - …, 2015 - Taylor & Francis
… of T cell immunity by B cell-based cancer vaccines. Numerous studies have investigated
the nature of TB cell interactions, but those studies mainly focused in the T cell-dependent …

[HTML][HTML] A guide to cancer immunotherapy: from T cell basic science to clinical practice

AD Waldman, JM Fritz, MJ Lenardo - Nature Reviews Immunology, 2020 - nature.com
… by adoptive transfer of CTLA4-bearing T reg cells to prevent autoimmunity induced by
CTLA4-deficient T cells that had been transferred to T cell- and B cell-deficient mice (Rag –/– mice…

Current advances in T-cell-based cancer immunotherapy

M Wang, B Yin, HY Wang, RF Wang - Immunotherapy, 2014 - Taylor & Francis
… Another group at Memorial Sloan-Kettering Cancer Center reported that five relapsed B
cell ALL patients with persistent morphological disease or minimal residual disease positive (…

Bispecific T‐cell engagers for cancer immunotherapy

AM Huehls, TA Coupet… - Immunology and cell …, 2015 - Wiley Online Library
… Blinatumomab is designed to target B cell-derived malignancies … T cells to CD19-positive
cell lines was demonstrated and was later demonstrated to facilitate elimination of B cells from …

Using antigen-specific B cells to combine antibody and T cell–based cancer immunotherapy

K Wennhold, M Thelen, HA Schlößer, N Haustein… - Cancer Immunology …, 2017 - AACR
… promising approach for cancer therapy. Here, we report that murine and human B cells with
a … for bifunctional cancer immunotherapy that combines B cell–mediated T-cell activation and …

[HTML][HTML] Cancer immunotherapy: Pros, cons and beyond

S Tan, D Li, X Zhu - Biomedicine & Pharmacotherapy, 2020 - Elsevier
… CD19 proteins, such as B-cell acute leukemia and large B-cell lymphoma. The drugs … rate
in non-small cell cancers, and KEYNOTE results showed that Pembrolizumab improved overall …

The double-edge role of B cells in mediating antitumor T-cell immunity: Pharmacological strategies for cancer immunotherapy

JZ Wang, YH Zhang, XH Guo, HY Zhang… - International …, 2016 - Elsevier
… Importantly, the involvement of B cells in cancer immunotherapy has been … role of B cells
in antitumor immunity and discusses their therapeutic implications in cancer immunotherapy. …

[HTML][HTML] Comprehensive analyses of tumor immunity: implications for cancer immunotherapy

B Li, E Severson, JC Pignon, H Zhao, T Li, J Novak… - Genome biology, 2016 - Springer
… of six immune cell types (B cells, CD4 T cells, CD8 T cells, neutrophil, macrophage, and
dendritic … The same phenomenon holds for renal clear cell cancer, where tumors with high TIM3 …

[HTML][HTML] Current perspectives in cancer immunotherapy

T Christofi, S Baritaki, L Falzone, M Libra, A Zaravinos - Cancers, 2019 - mdpi.com
immunotherapies against melanoma, non–small cell lung cancer (NSCLC) and renal cell
cancer … The ICOS-ICOS-L interaction can also induce the excretion of antibodies by B cells. It …