… , central composite design (CCD) has not previously been applied toward the … designs in
the optimization processCitation23. In this study, CCD was used for optimization of buccal films …

… potential application in pharmaceutical industry. The aim of this study is to develop buccal
films with A. arguta fruit extract as active ingredient to prevent OM symptoms. The films were …

… Buccal films are polymeric matrices designed to be … Conventionally, buccal films for biologics
are manufactured by solvent … -loaded mucoadhesive films as buccal drug delivery systems…

… film was wetted with phosphate buffer pH6.8 and it was pasted to the sheep buccal tissue with
finger tip by applying a … stirring rate was applied to simulate the buccal cavity environment. …

… films are designed for immediate disintegration, usually followed by swallowing of the active
pharmaceutical ingredient (API) together with saliva, buccal films are designed to adhere to …

… Design and characterization of mucoadhesive buccal patches containing cetylpyridinium
chloride. Acta Pharm., 2003; 53:199-212. Pandya P, Gattani S, Jain P, Khirwal L, Surana S. …

… a controlled release mucoadhesive buccal film containing HA as a … HA films are prepared by
applying freeze and thaw cross … × 4 1 factorial design was applied to study the effect of three …

… application. Saliva samples (~1.0 ml) were collected periodically first every half an hour and
then every hour for up to 6 h after film application… In this study, factorial design technique was …

… was to develop mouth dissolving film formulation of salbutamol sulfate for oral administration
with application of simplex lattice design. Experimental design methodology is the strategy …

… It is likely however that printed film designs with lower molecular weight stable biotech
payloads including lipophilic glucagon-like 1 (GLP-1) agonists and macrocycles with long half-…