… fabrication of fast dissolving buccal film of clonidine hydrochloride by employing quality by …
film-forming polymer (HPMC E 15) and plasticizer (PEG 400) as CMAs for formulation of films. …

… clonidine mucoadhesive buccal tablet (MBT) is a novel delivery system resulting in high and
sustained concentrations of clonidine in the oral … clonidine MBT with a reference oral tablet (…

… The incidence of detachment of the MBT within the 6 hours after application was 15% in all
patients, and 6.3% of the buccal tablet had to be replaced overall. Compliance according to …

… and pharmacologically similar to clonidine and other α … buccal tablet against the buccal
mucosa for about 1 min. For the purpose of the photography proof, in one volunteer, buccal tablet …

… validation of a stable paediatric oral formulation of clonidine hydrochloride 50 μg/ml, … of
clonidine hydrochloride was assessed using a validated HPLC method. Clonidine hydrochloride …

… Clonidine hydrochloride (CH) is an α-receptor agonist with anti-hypertensive and pain-… tablet
of CH (Kapvay®) was approved by the Food and Drug Administration (FDA) of USA [1]. Oral …

… Instantly dissolving buccal films have gained attention owing … Dapoxetine hydrochloride
(DPX) has a low oral … the formulation of instantly dissolving buccal films comprising a pH modifier …

… Blood pressure begins to decrease within 30-60 minutes after an oral dose of clonidine
hydrochloride, the maximum decrease occurs in approximately 2-4 hours. The hypotensive effect …

… It is structurally and pharmacologically similar to clonidine and other α2adrenergic agonists.
… of the buccal tablet on freshly cut sheep buccal mucosa. The fresh sheep buccal mucosa …

… In this work the FTIR data presented earlier suggest that clonidine hydrochloride interacts
with PVA and not SCMC in the tested films. This supports the suggestion that the carboxylic …