Development of Budesonide Microparticles Using Spray-Drying Technology for Pulmonary Administration: Design, Characterization, In Vitro Evaluation, and In Vivo …
SR Naikwade, AN Bajaj, P Gurav, MM Gatne… - AAPS …, 2009 - Springer
… the in vivo efficacy of budesonide (BUD) microparticles prepared by spray-… for pulmonary
administration with sustained-release profile and improved respirable fraction. Microspheres …
administration with sustained-release profile and improved respirable fraction. Microspheres …
Recent advances in the development of microparticles for pulmonary administration
H Jain, A Bairagi, S Srivastava, SB Singh… - Drug discovery today, 2020 - Elsevier
… microparticles of budesonide using a spray freeze-drying method. They developed micronized
porous particles of budesonide … microparticles of parathyroid hormone for pulmonary …
porous particles of budesonide … microparticles of parathyroid hormone for pulmonary …
Sustained therapeutic efficacy of budesonide-loaded chitosan swellable microparticles after lung delivery: Influence of in vitro release, treatment interval and dose
L Zhang, L Yang, X Zhang, L Jiaqi, L Fan… - Journal of Controlled …, 2018 - Elsevier
… , budesonide-loaded swellable microparticles with different in vitro release profiles were
administered … The encouraging results made after a single administration of budesonide-loaded …
administered … The encouraging results made after a single administration of budesonide-loaded …
Preparation and in vitro evaluation of budesonide spray dried microparticles for pulmonary delivery
S Naikwade, A Bajaj - Scientia Pharmaceutica, 2009 - mdpi.com
… The aim of inhaled administration of corticosteroids in respiratory disease is to achieve … for
budesonide [31, 32] and an increase in the dose and frequency of budesonide administration …
budesonide [31, 32] and an increase in the dose and frequency of budesonide administration …
Interest of cyclodextrins in spray-dried microparticles formulation for sustained pulmonary delivery of budesonide
G Dufour, W Bigazzi, N Wong, F Boschini… - International journal of …, 2015 - Elsevier
… Lung administration of therapeutic compounds is a challenging research field both for
systemic absorption and topical therapy. Dry powder inhalers are widely used to deliver drug …
systemic absorption and topical therapy. Dry powder inhalers are widely used to deliver drug …
Optimization of budesonide-loaded large-porous microparticles for inhalation using quality by design approach
L Zhang, X Zhang, J Li, M Beck-Broichsitter… - Journal of Drug Delivery …, 2019 - Elsevier
… for the development of budesonide (BUD)-loaded large porous microparticles (LPPs) for …
Route of administration Lung administration A newly developed route of administration to …
Route of administration Lung administration A newly developed route of administration to …
Preparation of budesonide-loaded porous PLGA microparticles and their therapeutic efficacy in a murine asthma model
YJ Oh, J Lee, JY Seo, T Rhim, SH Kim, HJ Yoon… - Journal of controlled …, 2011 - Elsevier
… DiI-loaded porous PLGA microparticles were administered to the mouse lung using a
Microspayer® Aerosolizer attached to a high-pressure syringe (Penn-Century). To confirm …
Microspayer® Aerosolizer attached to a high-pressure syringe (Penn-Century). To confirm …
Solid lipid budesonide microparticles for controlled release inhalation therapy
… phosphate buffer or simulated lung fluid. Comparison of the dissolution rates of crystalline
and amorphous budesonide, using either phosphate buffer or simulated lung fluid, suggested …
and amorphous budesonide, using either phosphate buffer or simulated lung fluid, suggested …
Preparation of high-performance ultrafine budesonide particles for pulmonary drug delivery
LM Xu, TT Hu, Y Pu, Y Le, JF Chen, JX Wang - Chemical Engineering …, 2014 - Elsevier
… In this work, a facile approach combining HPH and SD to prepare fine uniform low-density
spherical budesonide microparticles suitable for inhalation without surfactants is reported. In …
spherical budesonide microparticles suitable for inhalation without surfactants is reported. In …
Budesonide nanocrystal-loaded hyaluronic acid microparticles for inhalation: In vitro and in vivo evaluation
T Liu, M Han, F Tian, D Cun, J Rantanen, M Yang - Carbohydrate polymers, 2018 - Elsevier
… The purpose of this study was to investigate the pulmonary retention and … via pulmonary
administration. We hypothesized that nanocrystal loaded inhalable HA microparticles could …
administration. We hypothesized that nanocrystal loaded inhalable HA microparticles could …
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