Approach to buprenorphine use for opioid withdrawal treatment in the emergency setting

DH Cisewski, C Santos, A Koyfman, B Long - The American Journal of …, 2019 - Elsevier
… transdermal fentanyl, … abuse potential of buprenorphine in the outpatient setting is
countered by the prescribing of combined delivery of naloxone in 4-to-1 (buprenorphine-to-naloxone) …

“Macrodosing” Sublingual Buprenorphine and Extended-release Buprenorphine in a Hospital Setting: 2 Case Reports

M Kahan, L Marion-Bellemare, J Samson… - Journal of addiction …, 2023 - journals.lww.com
buprenorphine/naloxone quickly stabilized fentanyl users … buprenorphine ER in the community
28 days later. He reports that since receiving buprenorphine ER, he has not used fentanyl

High-dose buprenorphine induction in the emergency department for treatment of opioid use disorder

AA Herring, AA Vosooghi, J Luftig… - JAMA network …, 2021 - jamanetwork.com
… The increasing prevalence of high-potency illicit opioids, such as fentanyl and fentanyl
analogues, … It is possible that high-dose induction using a combination buprenorphine-naloxone

Buprenorphine precipitated opioid withdrawal: Prevention and management in the ED setting

A Spadaro, B Long, A Koyfman, J Perrone - The American journal of …, 2022 - Elsevier
… or the opioid antagonists naltrexone and naloxone [12]. … buprenorphine was started within
48 h of last fentanyl use compared to starting buprenorphine within 48 h of last methadone use

New developments in the management of opioid dependence: focus on sublingual buprenorphinenaloxone

M Soyka - Substance abuse and rehabilitation, 2015 - Taylor & Francis
… with naloxone. A diminished risk of diversion and abuse for the buprenorphinenaloxone
of other opioids, including methadone, buprenorphine (BUP), oxycodone, and fentanyl. …

The OPTIMA study, buprenorphine/naloxone and methadone models of care for the treatment of prescription opioid use disorder: study design and rationale

ME Socias, K Ahamad, B Le Foll, R Lim… - Contemporary Clinical …, 2018 - Elsevier
… opiates, including morphine, oxycodone, fentanyl, methadone and its metabolite (EDDP),
tramadol, buprenorphine, as well as for other common drugs used for non-medical purposes or …

[HTML][HTML] The epidemic of fentanyl misuse and overdoses: challenges and strategies

ND Volkow - World Psychiatry, 2021 - ncbi.nlm.nih.gov
… repeated fentanyl use might necessitate higher doses of methadone or buprenorphine than
… shorter duration of the action of naloxone (t 1/2 : 1.3‐2.4 hours) than that of fentanyl (t 1/2 : 7 …

The role of take-home naloxone in the epidemic of opioid overdose involving illicitly manufactured fentanyl and its analogs

HK Kim, NJ Connors… - Expert opinion on drug …, 2019 - Taylor & Francis
fentanyl analogs that are used as adulterants of the illicit drug supply and in counterfeit tablets.
It does not address fentanyl … This observation has been attributed to buprenorphine’s high …

[HTML][HTML] Overdose following initiation of naltrexone and buprenorphine medication treatment for opioid use disorder in a United States commercially insured cohort

JR Morgan, BR Schackman, ZM Weinstein… - Drug and alcohol …, 2019 - Elsevier
… mono-buprenorphine for cost or medical (such as pregnancy or sensitivity to naloxone) …
This is particularly important given the increasing presence of fentanyl, which may make it …

Current knowledge of buprenorphine and its unique pharmacological profile

J Pergolizzi, AM Aloisi, A Dahan, J Filitz… - Pain …, 2010 - Wiley Online Library
… , the ability of naloxone to reverse buprenorphine-induced … of transdermal fentanyl and
transdermal buprenorphine in … using ratios of 1:100 and 1:75 for fentanyl and buprenorphine, …