Dacomitinib in lung cancer: a “lost generation” EGFR tyrosine-kinase inhibitor from a bygone era?
SHI Ou, RA Soo - Drug design, development and therapy, 2015 - Taylor & Francis
… mutations in non-small-cell lung cancer (NSCLC) in 2004 heralded the era of molecular
classification of lung cancer and precision cancer medicine in lung cancer. Citation1 – Citation3 …
classification of lung cancer and precision cancer medicine in lung cancer. Citation1 – Citation3 …
Treatment of Lung Cancer in the New Era
G Maheshwari, BP Chauhan, S Dang… - … in Anti-Cancer Drug …, 2020 - books.google.com
… Lung cancer or lung carcinoma is defined as the uncontrolled proliferation of normal lung
cells due to the genetic damage and it has the capacity to invade the neighboring tissues and …
cells due to the genetic damage and it has the capacity to invade the neighboring tissues and …
[HTML][HTML] Review of ongoing clinical trials in non-small cell lung cancer: a status report for 2009 from the ClinicalTrials. gov website
J Subramanian, AR Madadi, M Dandona… - Journal of Thoracic …, 2010 - Elsevier
… The current model may have served us well in the bygone era dominated only by cytotoxic
chemotherapies. Clinical trial processes for cancer therapy in general and NSCLC in …
chemotherapies. Clinical trial processes for cancer therapy in general and NSCLC in …
[HTML][HTML] Tyrosine kinase inhibitors for the treatment of EGFR mutation-positive non–small-cell lung cancer: a clash of the generations
R Shah, JF Lester - Clinical lung cancer, 2020 - Elsevier
… Non–small-cell lung cancer (NSCLC) is the leading cause of cancer mortality worldwide.
Because most patients will have a diagnosis of advanced disease, localized intervention will …
Because most patients will have a diagnosis of advanced disease, localized intervention will …
Next-generation EGFR/HER tyrosine kinase inhibitors for the treatment of patients with non-small-cell lung cancer harboring EGFR mutations: a review of the …
X Wang, D Goldstein, PJ Crowe… - OncoTargets and …, 2016 - Taylor & Francis
Full article: Next-generation EGFR/HER tyrosine kinase inhibitors for the treatment of patients
with non-small-cell lung cancer harboring EGFR mutations: a review of the evidence Skip …
with non-small-cell lung cancer harboring EGFR mutations: a review of the evidence Skip …
Maximum tolerated dose: clinical endpoint for a bygone era?
CH Takimoto - Targeted oncology, 2009 - Springer
… Gefitinib, the small molecule inhibitor of the epidermal growth factor receptor (EGFR), was
tested in a randomized phase II study in lung cancer patients using two different dose levels, …
tested in a randomized phase II study in lung cancer patients using two different dose levels, …
Clinical Experience With 75-mg Dose of Erlotinib for Mutated Metastatic EGFR Non-small Cell Lung Cancer
O Aren, S Samtani, M Frelinghuysen… - American Journal of …, 2021 - journals.lww.com
… Non-small cell lung cancer (NSCLC) remains the leading cause of cancer death worldwide,
although important advances in target therapy have been developed in the past few years. …
although important advances in target therapy have been developed in the past few years. …
Tobacco" plain packaging" policy-unlearnt lessons of a bygone era: intellectual property
D Momberg - Without Prejudice, 2014 - journals.co.za
… of lung cancer in those very soldiers who had served in the trenches. At first they thought the
rise in the incidents of lung cancer … correlation between smoking and lung cancer, than was …
rise in the incidents of lung cancer … correlation between smoking and lung cancer, than was …
Discovery of novel thiazolyl-pyrazolines as dual EGFR and VEGFR-2 inhibitors endowed with in vitro antitumor activity towards non-small lung cancer
EA Abdelsalam, AA Abd El-Hafeez… - Journal of enzyme …, 2022 - Taylor & Francis
… The best anti-proliferative activity for the examined thiazolyl-pyrazolines was observed
against the non-small lung cancer cells (NSCLC). Compounds 10b and 10d displayed …
against the non-small lung cancer cells (NSCLC). Compounds 10b and 10d displayed …
[HTML][HTML] Efficacy of first-line erlotinib in non-small cell lung cancer patients undergoing dose reduction and those with a low body surface area: A population-based …
M Inagaki, Y Shinohara… - Molecular and …, 2016 - spandidos-publications.com
… This retrospective population-based study included patients with non-small cell lung cancer
(… Pathological diagnosis of lung cancer was defined by the World Health Organization …
(… Pathological diagnosis of lung cancer was defined by the World Health Organization …
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