Dietary restriction in C. elegans: from rate-of-living effects to nutrient sensing pathways

G Walker, K Houthoofd, JR Vanfleteren… - Mechanisms of ageing …, 2005 - Elsevier
… The nematode Caenorhabditis elegans has been subjected to dietary restriction (DR) by a
number of means, with varying results in … In this review, we discuss recent developments in C. …

Dietary Restriction in the Nematode Caenorhabditis elegans

K Houthoofd, TE Johnson… - The Journals of …, 2005 - academic.oup.com
elegans. In this review we discuss the difficulties of subjecting C. elegans to dietary restriction,
the effects of dietary restriction on metabolism and stress defense, and the potential role of …

The longevity effect of dietary restriction in Caenorhabditis elegans

K Houthoofd, JR Vanfleteren - Experimental gerontology, 2006 - Elsevier
… Food restriction has also been found to increase life span in … , the nematode worm
Caenorhabditis elegans and the fruit fly … isocaloric diet with a reduction of specific nutrients, or a …

Different dietary restriction regimens extend lifespan by both independent and overlapping genetic pathways in C. elegans

EL Greer, A Brunet - Aging cell, 2009 - Wiley Online Library
Dietary restriction (DR) has the remarkable ability to extend lifespan and healthspan. A …
longevity by different DR regimens in Caenorhabditis elegans. We have previously shown that …

Dietary restriction in C. elegans: recent advances

JR Cypser, D Kitzenberg, SK Park - Experimental gerontology, 2013 - Elsevier
… The nematode Caenorhabditis elegans continues to serve as a useful model of life extension
caused by dietary restriction. Using this model, downstream effectors of dietary restriction-…

Two neurons mediate diet-restriction-induced longevity in C. elegans

NA Bishop, L Guarente - Nature, 2007 - nature.com
diet-restricted longevity has been demonstrated. Here we show that increased longevity of
diet-restricted Caenorhabditis elegansDietary restriction activates skn-1 in these two neurons…

Dietary restriction in the nematode Caenorhabditis elegans

K Houthoofd, D Gems, TE Johnson… - … of dietary restriction in …, 2007 - karger.com
The nematode Caenorhabditis elegans has proved to be an excellent model organism for the
… seems surprising that dietary restriction (DR) has not been extensively studied using C. …

[HTML][HTML] Age- and calorie-independent life span extension from dietary restriction by bacterial deprivation in Caenorhabditis elegans

ED Smith, TL Kaeberlein, BT Lydum, J Sager… - BMC developmental …, 2008 - Springer
… , we propose that dietary restriction by bacterial deprivation increases longevity in C. …
Dietary restriction (DR), also referred to as calorie restriction, is an intervention that extends life …

Dietary Restriction in C. elegans

Y Zhang, WB Mair - Ageing: Lessons from C. elegans, 2017 - Springer
elegans intervention testing program accelerates small molecule discovery, worms will
continue to be at the forefront of our understanding of dietary restriction. Exciting times lay ahead. …

Dietary deprivation extends lifespan in Caenorhabditis elegans

GD Lee, MA Wilson, M Zhu, CA Wolkow… - Aging cell, 2006 - Wiley Online Library
Dietary restriction (DR) is well known as a nongenetic intervention that robustly extends …
We have found in Caenorhabditis elegans that dietary deprivation (DD) during adulthood, …